Development of a three dimensional (3D) knitted scaffold for myocardial tissue engineering. Part II: biological performance of the knitted scaffolds

Author(s):  
Derya Haroglu ◽  
Ahmet Eken ◽  
Zeynep Burçin Gönen ◽  
Dilek Bahar
2020 ◽  
Vol 58 (3) ◽  
pp. 500-510 ◽  
Author(s):  
Christopher D Roche ◽  
Russell J L Brereton ◽  
Anthony W Ashton ◽  
Christopher Jackson ◽  
Carmine Gentile

Abstract Summary Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells.


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