RESEARCH OF OPTIMUM CONDITIONS FOR EXTRACTION OF METAL COMPLEXES BY ALKYLIMIDAZOLE. PART V. THE INFLUENCE OF ALKYL SUBSTITUENTS AT POSITIONS 4 AND 5 OF THE IMIDAZOLE RING ON EXTRACTABILITY OF THE METAL COMPLEXES

1994 ◽  
Vol 12 (4) ◽  
pp. 687-699 ◽  
Author(s):  
Krystyna Kurdziel
Keyword(s):  
Metal Complexes ◽  
Imidazole Ring ◽  
Optimum Conditions

scholarly journals Synthesis, Spectroscopic, Calculated and Thermal Study of Copper and Cobalt Complexes with Dacarbazine

2021 ◽  
Author(s):  
Grzegorz Świderski ◽  
Ryszard Łaźny ◽  
Michał Sienkiewicz ◽  
Monika Kalinowska ◽  
Renata Świsłocka ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Alkylating Agents ◽  
Imidazole Ring ◽  
Spectroscopic Properties ◽  
Electronic Charge ◽  
Dft Methods ◽  
3D Metal Complexes ◽  
Homo And Lumo ◽  
Ft Ir ◽  
Thermal Stability Of

: Dacarbazine, DAC, 5-(3,3-dimethyltriazeno)imidazol-4-carboxamideis is an imidazole-carboxamide derivative, that is structurally related to purines. DAC belongs to the triazene compounds, which are a group of alkylating agents with antitumour and mutagenic properties. DAC is a non-cell cycle specific drug, active on all phases of cellular cycle. In the frame of this work the 3d-metal complexes (cobalt and copper) with dacarbazine were synthesized. Their spectroscopic properties by the use of FT-IR, FT-Raman and 1HNMR were studied. The structures of dacarbazine and its complexes with copper(II) and cobalt(II) were calculated using DFT methods. The effect of metals on the electronic charge distribution of dacarbazine was discussed on the basis of calculated NBO atomic charges. The reactivity of metal complexes in relation to ligand alone was estimated on the basis of calculated energy of HOMO and LUMO orbitals. The aromaticity of imidazole ring in dacarbazine and the complexes was compared (on the basis of calculated geometric indices of aromaticity). Thermal stability of the investigated 3d-metal complexes with dacarbazine and the products of their thermal decomposition were analyzed.

scholarly journals Synthesis, Spectroscopic, and Theoretical Study of Copper and Cobalt Complexes with Dacarbazine

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3274
Author(s):  
Grzegorz Świderski ◽  
Ryszard Łaźny ◽  
Michał Sienkiewicz ◽  
Monika Kalinowska ◽  
Renata Świsłocka ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Alkylating Agents ◽  
Imidazole Ring ◽  
Spectroscopic Properties ◽  
Electronic Charge ◽  
Dft Methods ◽  
3D Metal Complexes ◽  
Homo And Lumo ◽  
Ft Ir ◽  
Thermal Stability Of

Dacarbazine (DAC) 5-(3,3-dimethyl-1-triazenyl)imidazole-4-carboxamide is an imidazole-carboxamide derivative that is structurally related to purines. DAC belongs to the triazene compounds, which are a group of alkylating agents with antitumor and mutagenic properties. DAC is a non-cell cycle specific drug, active in all phases of the cellular cycle. In the frame of this work the 3d metal complexes (cobalt and copper) with dacarbazine were synthesized. Their spectroscopic properties by the use of FT-IR, FT-Raman, and 1HNMR were studied. The structures of dacarbazine and its complexes with copper(II) and cobalt(II) were calculated using DFT methods. The effect of metals on the electronic charge distribution of dacarbazine was discussed on the basis of calculated NBO atomic charges. The reactivity of metal complexes in relation to ligand alone was estimated on the basis of calculated energy of HOMO and LUMO orbitals. The aromaticity of the imidazole ring in dacarbazine and the complexes were compared (on the basis of calculated geometric indices of aromaticity). Thermal stability of the investigated 3d-metal complexes with dacarbazine and the products of their thermal decomposition were analyzed.

Mononuclear transition metal complexes containing iodo-imidazole ring endowed with potential anti-Candida activity

2016 ◽  
Vol 25 (11) ◽  
pp. 2557-2566 ◽  
Author(s):  
Mohmmad Younus Wani ◽  
Aijaz Ahmad ◽  
Manzoor Ahmad Malik ◽  
Abilio J.F.N. Sobral
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Imidazole Ring

Mechanochemical changes on cyclometalated Ir(iii) acyclic carbene complexes – design and tuning of luminescent mechanochromic transition metal complexes

2020 ◽  
Vol 7 (3) ◽  
pp. 786-794 ◽  
Author(s):  
Jingqi Han ◽  
Kin-Man Tang ◽  
Shun-Cheung Cheng ◽  
Chi-On Ng ◽  
Yuen-Kiu Chun ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Carbene Complexes ◽  
New Class

A new class of luminescent cyclometalated Ir(iii) complexes with readily tunable mechanochromic properties derived from the mechanically induced trans-to-cis isomerization have been developed.

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