13q Deletion in Chronic Lymphocytic Leukemia: Characterization of E4.5, a Novel Chromosome Condensation Regulator-like Guanine Nucleotide Exchange Factor

2003 ◽  
Vol 44 (9) ◽  
pp. 1579-1585 ◽  
Author(s):  
E.E. Solomou ◽  
P.P. Sfikakis ◽  
P. Kotsi ◽  
M. Papaioannou ◽  
V. Karali ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Guanine Nucleotide Exchange Factor ◽  
Chromosome Condensation ◽  
Lymphocytic Leukemia ◽  
Guanine Nucleotide ◽  
Nucleotide Exchange ◽  
Guanine Nucleotide Exchange ◽  
Nucleotide Exchange Factor ◽  
13Q Deletion

scholarly journals Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

2011 ◽  
Vol 6 ◽  
pp. 11 ◽  
Author(s):  
Joseph E Aslan ◽  
Alex M Spencer ◽  
Cassandra P Loren ◽  
Jiaqing Pang ◽  
Heidi C Welch ◽  
...  
Keyword(s):  
Guanine Nucleotide Exchange Factor ◽  
Guanine Nucleotide ◽  
Nucleotide Exchange ◽  
Exchange Factor ◽  
Guanine Nucleotide Exchange ◽  
Nucleotide Exchange Factor

scholarly journals Calcium-RasGRP2-Rap1 signaling mediates CD38-induced migration of chronic lymphocytic leukemia cells

2018 ◽  
Vol 2 (13) ◽  
pp. 1551-1561 ◽  
Author(s):  
Silvia Mele ◽  
Stephen Devereux ◽  
Andrea G. Pepper ◽  
Elvira Infante ◽  
Anne J. Ridley
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Guanine Nucleotide ◽  
Nucleotide Exchange ◽  
Cd38 Expression ◽  
Guanine Nucleotide Exchange ◽  
Nucleotide Exchange Factor ◽  
Key Points ◽  
And Migration

Key Points Basal intracellular Ca2+ levels and migration increase with higher CD38 expression in CLL cells. Rap1 and the Rap1 guanine-nucleotide exchange factor RasGRP2 are required for CLL migration and regulated by CD38 levels.

Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1

FEBS Letters ◽  
1999 ◽  
Vol 457 (1) ◽  
pp. 85-89 ◽  
Author(s):  
Tamotsu Ichiba ◽  
Yasutaka Hoshi ◽  
Yoshikatsu Eto ◽  
Naoko Tajima ◽  
Yasunobu Kuraishi
Keyword(s):  
Guanine Nucleotide Exchange Factor ◽  
Guanine Nucleotide ◽  
Nucleotide Exchange ◽  
Exchange Factor ◽  
Guanine Nucleotide Exchange ◽  
Nucleotide Exchange Factor
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