Cytotoxic and apoptotic activities of novel Pd(II) complexes against human leukemia cell lines in vitro

2017 ◽  
Vol 54 (5) ◽  
pp. 263-270 ◽  
Author(s):  
Neslihan Tekin ◽  
Kamile Öztürk ◽  
Talat Baran ◽  
Barış Kerimoğlu ◽  
Mehtap Tarhan ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines

In vitro radiosensitivity of human leukemia cell lines.

Radiology ◽  
1981 ◽  
Vol 139 (2) ◽  
pp. 485-487 ◽  
Author(s):  
R R Weichselbaum ◽  
J S Greenberger ◽  
A Schmidt ◽  
A Karpas ◽  
W C Moloney ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines

scholarly journals Apoptosis Induction in Human Leukemia Cell Lines by Gold Nanoparticles Synthesized Using the Green Biosynthetic Approach

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Farideh Namvar ◽  
Heshu Sulaiman Rahman ◽  
Rosfarizan Mohamad ◽  
Abdullah Rasedee ◽  
Swee Keong Yeap ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cell Lines ◽  
Leukemia Cell ◽  
Water Extract ◽  
Human Leukemia ◽  
Cytotoxicity Test ◽  
Apoptosis Induction ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines

Gold nanoparticles were grown onSargassum muticumwater extract (S-GNPs) using the green biosynthetic approach. The nanoparticles were characterized using UV-visible spectroscopy, zeta potential, and transmission electron microscopy (TEM). The resulting S-GNPs were spherical and crystalline with a size of <10 nm. Thein vitroanticancer activity was demonstrated in human leukemia cell lines. The cancer cells were treated with different concentrations of S-GNPs, and calorimetric (MTT) assay used for the cytotoxicity test, which resulted in an IC50value of 4.22 ± 1.12, 5.71 ± 1.4, 6.55 ± 0.9, and 7.29 ± 1.7 μg/mL for each of the K562, HL-60, Jurkat, and CEM-ss cells, respectively. Thus, the K562 was selected for the next experiments. Furthermore, apoptosis induction was confirmed by Hoechst 33342, annexin V staining, and caspase-3/-9 activity tests. The cell cycle analysis exhibited a significant increase in the accumulation of S-GNPs treated cells at the sub-G1 phase, demonstrating the induction of apoptosis by S-GNPs. The nature of the inhibition of cancer cell growth by S-GNPs could open the way for further research in the design of green synthesis therapeutic agents, particularly in nanomedicine, for the treatment of cancer.

scholarly journals Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro

Leukemia ◽  
2002 ◽  
Vol 16 (9) ◽  
pp. 1808-1817 ◽  
Author(s):  
M Akutsu ◽  
Y Furukawa ◽  
S Tsunoda ◽  
T Izumi ◽  
K Ohmine ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines ◽  
Synergism And Antagonism

Effects of carboplatin in combination with other anticancer agents on human leukemia cell lines

1993 ◽  
Vol 17 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Yasuhiko Kano ◽  
Miyuki Akutsu ◽  
Kenichi Suzuki ◽  
Minoru Yoshida
Keyword(s):  
Cell Lines ◽  
Anticancer Agents ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines

Antitumor and apoptotic effects of new-generation platinum compounds on human leukemia cell lines HL-60 and K562

Biologia ◽  
2021 ◽  
Author(s):  
Neslihan Tekin Karacaer ◽  
Barış Kerimoğlu ◽  
Talat Baran ◽  
Mehtap Tarhan ◽  
Ayfer Menteş ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Platinum Compounds ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines ◽  
New Generation ◽  
Apoptotic Effects

Evaluation of theIn VitroAntiproliferative Properties of Four Novel Anthracyclines YM1, 3, 4 and 6 in Human Leukemia Cell Lines

1992 ◽  
Vol 4 (5) ◽  
pp. 306-311 ◽  
Author(s):  
X.R. Jiang ◽  
A.C. Newland ◽  
M.G. Macey ◽  
G.C. Jenkins ◽  
T. Miki ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines

Effect of sodium dichloroacetate on apoptotic gene expression in human leukemia cell lines

2019 ◽  
Vol 71 (2) ◽  
pp. 248-256 ◽  
Author(s):  
Jagoda Abramek ◽  
Jacek Bogucki ◽  
Marta Ziaja-Sołtys ◽  
Andrzej Stępniewski ◽  
Anna Bogucka-Kocka
Keyword(s):  
Gene Expression ◽  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Apoptotic Gene ◽  
Leukemia Cell Lines
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