Patients’ perspectives on a drug safety monitoring system for immune-mediated inflammatory diseases based on patient-reported outcomes

Background: The prevalence of anxiety is three times greater in patients with chronic diseases than in the general population. There has recently been growing interest in the roles of inflammation in contributing to the development of anxiety in people with Immune-mediated inflammatory diseases (IMID). Patient-reported outcome measures can facilitate the assessment of physical and psychological functioning. In recent years various patient outcome measures (PROMs) have been implemented. The National Institutes of Health (NIH)'s Patient-Reported Outcomes Measurement Information System (PROMIS®) is a set of publicly available and standardized Patient-Reported Outcomes (PROs) that cover physical appearance, mental health, and social health. The PROMIS® has been built through an Item Response Theory approach (IRT), a model-based measurement in which trait level estimates depend on both persons' responses and on the properties of the items that were administered. The aim of this study is to test the psychometric properties of the original anxiety items of the PROMIS® in a cohort of outpatients with IMIDs.Methods: We translated the original eight anxiety items from the PROMIS into Italian and administered them to consecutive outpatients affected by Inflammatory Bowel disease (n = 246), rheumatological (n = 100) and dermatological (n = 43) diseases, and healthy volunteers (n = 280). We analyzed the data through an Item Response Theory (IRT) analysis to evaluate the psychometric properties of the Italian adaptation of the PROMIS® anxiety short form.Results: Taken together, Confirmatory Factor Analysis and Exploratory Factor analysis suggested that the unidimensionality assumption if the instrument holds. The instrument has excellent reliability from a Classical Theory of Test (CTT) standpoint (Cronbach's ⍺ = .94, McDonald's ω = .95). The 1PL Graded Response Model (GRM) model provided a good balance between the goodness of fit and parsimony (BIC = 9099.82) as compared to the 2PL GRM model (BIC = 9111.02). We did not find signs of Differential Item Functioning (DIF), but we found that the local independence assumption was violated for some items. The analysis of the test reliability curve suggested that the instrument is most reliable for higher levels of the latent trait of anxiety.Discussion: The Italian adaptation of the PROMIS® anxiety short form shows acceptable psychometric properties both from a CTT and an IRT standpoint. Its compatibility with the 1 parameter logistic (1PL) model implies that its total score is a sufficient statistic for the latent anxiety trait. The TRC shows that this instrument is mostly informative for people with higher levels of anxiety, making it particularly suitable for clinical populations such as IMID patients.

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A brief analysis of electromagnetic interference in the underground coal mine safety monitoring system

Information Technology and Industrial Engineering ◽

10.2495/itie130421 ◽

2013 ◽

Cited By ~ 1

Author(s):

Xingzhi Hu ◽

Jikun Wang ◽

Xuezhe Li ◽

Feiji Ding

Keyword(s):

Monitoring System ◽

Coal Mine ◽

Electromagnetic Interference ◽

Safety Monitoring ◽

Mine Safety ◽

Underground Coal Mine ◽

Coal Mine Safety ◽

Safety Monitoring System

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Research on Construction and Function of Safety Monitoring Sys- tem for Integrated Construction Site Based on BIM

Journal of Architectural Research and Development ◽

10.26689/jard.v1i1.97 ◽

1970 ◽

Vol 1 (1) ◽

Author(s):

Dan Xin

Keyword(s):

Monitoring System ◽

Safety Management ◽

Safety Monitoring ◽

Information Collection ◽

Construction Site ◽

Management Efficiency ◽

Lack Of Information ◽

Safety Monitoring System ◽

And Function

The effective construction of safety monitoring system at construction site depends on perfect management system and advanced technical support. And the lack of information technology platform, resulting in reduced management efficiency, information is not accurate and other issues. Based on the construction site safety monitoring system to achieve the goal, to do a good job in advance prevention, to take the latest information collection technology RFID and BIM integrated comprehensive and effective monitoring of the construction site, constitute the main technology in the monitoring system, thus ensuring the construction site safety monitoring efficiency , Comprehensive, real-time, etc., on the management and technical two points to achieve the construction site safety monitoring, improve the quality of safety management.

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