A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud

2019 ◽  
Vol 34 (21) ◽  
pp. 3027-3035 ◽  
Author(s):  
Tiwalade A. Adelakun ◽  
Xiao Ding ◽  
Rose M. Ombati ◽  
Ning-Dong Zhao ◽  
Obiageri O. Obodozie-Ofoegbu ◽  
...  
Keyword(s):  
Phorbol Ester ◽  
Euphorbia Fischeriana

A role for protein kinase Cε in the inhibition of apical Cl−1/OH− exchange activity in Caco2 cells by phorbol ester PMA

2001 ◽  
Vol 120 (5) ◽  
pp. A528-A528
Author(s):  
S SAKSENA ◽  
R GILL ◽  
S TYAGI ◽  
I SYED ◽  
A CHINNAKOTLA ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Phorbol Ester ◽  
Caco2 Cells ◽  
Exchange Activity

Studies of the Factor Xa-Dependent Inhibitor of Factor VIIa/Tissue Factor (Extrinsic Pathway Inhibitor) from Cell Supernates of Cultured Human Umbilical Vein Endothelial Cells

1989 ◽  
Vol 61 (01) ◽  
pp. 101-105 ◽  
Author(s):  
Bonnie J Warn-Cramer ◽  
Fanny E Almus ◽  
Samuel I Rapaport
Keyword(s):  
Molecular Weight ◽  
Endothelial Cells ◽  
Tissue Factor ◽  
Phorbol Ester ◽  
Umbilical Vein ◽  
Primary Cultures ◽  
Factor Xa ◽  
Extrinsic Pathway ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

SummaryCultured human umbilical vein endothelial cells (HUVEC) have been reported to produce extrinsic pathway inhibitor (EPI), the factor Xa-dependent inhibitor of factor VHa/tissue factor (TF). We examined the release of this inhibitor from HUVEC as a function of their growth state and in response to the induction of endothelial cell TF activity. HUVEC constitutively produced significant amounts of EPI at all stages of their growth in culture including the post-confluent state. Rate of release varied over a 3-fold range for primary cultures from 12 different batches of pooled umbilical cord cells. Constitutive EPI release was unaltered during a 6 hour period of induction of TF activity with thrombin or phorbol ester but slowed during longer incubation of the cells with phorbol ester. Whereas plasma contains two molecular weight forms of EPI, only the higher of these two molecular weight forms was demonstrable by Western analysis of HUVEC supernatants with 125I-factor Xa as the ligand.

Diterpenes and Triterpenes from the Roots of Euphorbia fischeriana

2010 ◽  
Vol 8 (2) ◽  
pp. 101-103 ◽  
Author(s):  
Qi-Cheng WU ◽  
Yu-Ping TANG ◽  
An-Wei DING ◽  
Fen-Qiang YOU ◽  
Jin-Ao DUAN
Keyword(s):  
Euphorbia Fischeriana

Chemical constituents of Euphorbia fischeriana

2012 ◽  
Vol 10 (4) ◽  
pp. 299-302 ◽  
Author(s):  
Xiao-Yang WANG ◽  
Li-Ping LIU ◽  
Ting-Guo KANG ◽  
Hong-Bing WANG
Keyword(s):  
Chemical Constituents ◽  
Euphorbia Fischeriana

Induction of Monocytic Differentiation by Tumor Necrosis Factor in Phorbol Ester-resistant KG-1a Cells

1990 ◽  
Vol 2 (10) ◽  
pp. 327-332 ◽  
Author(s):  
Surender Kharbanda ◽  
Takashi Nakamura ◽  
Rakesh Datta ◽  
Matthew L. Sherman ◽  
Kufe Donald
Keyword(s):  
Tumor Necrosis Factor ◽  
Phorbol Ester ◽  
Tumor Necrosis ◽  
Monocytic Differentiation ◽  
Necrosis Factor

Effects of phorbol ester and dexamethasone treatment on histidine decarboxylase and ornithine decarboxylase in basophilic cells

2001 ◽  
Vol 61 (9) ◽  
pp. 1101-1106 ◽  
Author(s):  
Ignacio Fajardo ◽  
Jose L Urdiales ◽  
Miguel A Medina ◽  
Francisca Sanchez-Jimenez
Keyword(s):  
Ornithine Decarboxylase ◽  
Phorbol Ester ◽  
Histidine Decarboxylase ◽  
Dexamethasone Treatment
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