scholarly journals Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR

Autophagy ◽  
2019 ◽  
Vol 15 (6) ◽  
pp. 998-1016 ◽  
Author(s):  
Bin Ye ◽  
Quan Wang ◽  
Haixia Hu ◽  
Yilin Shen ◽  
Cui Fan ◽  
...  
Keyword(s):  
Nuclear Translocation ◽  
Spiral Ganglion ◽  
Ganglion Neuron ◽  
Spiral Ganglion Neuron ◽  
Autophagic Flux ◽  
Neuron Degeneration ◽  
Cochlear Spiral Ganglion

miR-204 suppresses cochlear spiral ganglion neuron survival in vitro by targeting TMPRSS3

2014 ◽  
Vol 314 ◽  
pp. 60-64 ◽  
Author(s):  
Youzhong Li ◽  
Anquan Peng ◽  
Shenglei Ge ◽  
Qin Wang ◽  
Jiajia Liu
Keyword(s):  
Spiral Ganglion ◽  
Ganglion Neuron ◽  
Spiral Ganglion Neuron ◽  
Neuron Survival ◽  
Cochlear Spiral Ganglion

scholarly journals Inner Hair Cell and Neuron Degeneration Contribute to Hearing Loss in a Dfna2-Like Mouse Model

2018 ◽  
Author(s):  
Camila Carignano ◽  
Esteban Pablo Barila ◽  
Ezequiel Ignacio Rías ◽  
Leonardo Dionisio ◽  
Eugenio Aztiria ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
Hair Cells ◽  
Spiral Ganglion ◽  
Outer Hair Cells ◽  
Ganglion Neuron ◽  
Spiral Ganglion Neuron ◽  
Inner Hair Cell ◽  
Neuron Degeneration ◽  
Knock Out

HIGHLIGHTSKCNQ4 knock-out mouse shows hair cells and spiral ganglion neuron degeneration.Inner hair cells and spiral ganglion neuron loss begin 30 weeks later than outer hair cells in Kcnq4-/- mice.Inner hair cell loss kinetic is faster than that of outer hair cells in cochlear basal turn in Kcnq4-/-.Outer hair cells from Kcnq4-/- mice degenerate slower in apical than in basal turn.Kcnq4 knock-out allele expressed in C3H/HeJ strain reproduces the two phases of DFNA2 hearing loss.GRAPHICAL ABSTRACT

Topographically Conductive Butterfly Wing Substrates for Directed Spiral Ganglion Neuron Growth

Small ◽  
2021 ◽  
pp. 2102062
Author(s):  
Hao Wei ◽  
Zhuoyue Chen ◽  
Yangnan Hu ◽  
Wei Cao ◽  
XiaoFeng Ma ◽  
...  
Keyword(s):  
Spiral Ganglion ◽  
Ganglion Neuron ◽  
Spiral Ganglion Neuron ◽  
Butterfly Wing ◽  
Neuron Growth

Intratympanic Steroid Prevents Long-Term Spiral Ganglion Neuron Loss in Experimental Meningitis

2010 ◽  
Vol 31 (3) ◽  
pp. 394-403 ◽  
Author(s):  
Lise Worsøe ◽  
Christian Thomas Brandt ◽  
Søren Peter Lund ◽  
Christian Østergaard ◽  
Jens Thomsen ◽  
...  
Keyword(s):  
Spiral Ganglion ◽  
Ganglion Neuron ◽  
Spiral Ganglion Neuron ◽  
Neuron Loss
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