Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor

Gut Microbes ◽

10.1080/19490976.2021.1938380 ◽

2021 ◽

Vol 13 (1) ◽

pp. 1938380

Author(s):

Ruth X. Wang ◽

Morkos A. Henen ◽

J. Scott Lee ◽

Beat Vögeli ◽

Sean P. Colgan

Keyword(s):

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase

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Hypoxia-Inducible Factor (HIF) Prolyl Hydroxylase Inhibitor FG-2216 Increases Hb Without FE Depletion in the Absence of IV FE

American Journal of Kidney Diseases ◽

10.1053/j.ajkd.2013.02.254 ◽

2013 ◽

Vol 61 (4) ◽

pp. B78

Keyword(s):

Hypoxia Inducible Factor ◽

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase

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Roxadustat. Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, treatment of anemia

Drugs of the Future ◽

10.1358/dof.2014.039.011.2185942 ◽

2014 ◽

Vol 39 (11) ◽

pp. 783

Author(s):

G. Virgili-López

Keyword(s):

Hypoxia Inducible Factor ◽

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase ◽

Inhibitor Treatment

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Effect of a HIF-prolyl hydroxylase inhibitor on aortic pressure, heart rate and peak right ventricular pressure in rats exposed to acute hypoxia

Journal of Pharmacological and Toxicological Methods ◽

10.1016/j.vascn.2016.02.141 ◽

2016 ◽

Vol 81 ◽

pp. 378

Author(s):

Loren Kohrs ◽

Jon Renninger ◽

Dennis Murphy

Keyword(s):

Right Ventricular ◽

Acute Hypoxia ◽

Aortic Pressure ◽

Prolyl Hydroxylase ◽

Ventricular Pressure ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase

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HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

Blood Advances ◽

10.1182/bloodadvances.2018017566 ◽

2019 ◽

Vol 3 (3) ◽

pp. 406-418 ◽

Author(s):

Kavita Bisht ◽

Marion E. Brunck ◽

Taichi Matsumoto ◽

Crystal McGirr ◽

Bianca Nowlan ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell ◽

Prolyl Hydroxylase ◽

Stem Cell Mobilization ◽

Hematopoietic Stem ◽

Hematopoietic Stem Cell Mobilization ◽

Prolyl Hydroxylase Inhibitor ◽

Cell Mobilization ◽

Hif Prolyl Hydroxylase ◽

Mouse Hematopoietic Stem Cell

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Overcoming bioanalytical challenges associated with the separation and quantitation of GSK1278863, a HIF-prolyl hydroxylase inhibitor, and its 14 stereoisomeric metabolites

Journal of Chromatography B ◽

10.1016/j.jchromb.2015.11.057 ◽

2016 ◽

Vol 1009-1010 ◽

pp. 7-16 ◽

Author(s):

Hermes Licea Perez ◽

Dana Knecht ◽

Christopher A. Evans

Keyword(s):

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase

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Vadadustat. Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, Treatment of anemia secondary to chronic kidney disease

Drugs of the Future ◽

10.1358/dof.2016.041.10.2523217 ◽

2016 ◽

Vol 41 (10) ◽

pp. 601

Author(s):

P. Cole

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Hypoxia Inducible Factor ◽

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase ◽

Inhibitor Treatment

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In response to “Title: Letter to the Editor in response to the article ‘Efficacy and safety of HIF prolyl hydroxylase inhibitor vs epoetin and darbepoetin for anemia in chronic kidney disease patients not undergoing dialysis: A network meta-analysis’”

Pharmacological Research ◽

10.1016/j.phrs.2020.105227 ◽

2020 ◽

pp. 105227

Author(s):

Qiyan Zheng ◽

Huisheng Yang ◽

Yu Ning Liu ◽

Wei Jing Liu

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Meta Analysis ◽

Prolyl Hydroxylase ◽

Efficacy And Safety ◽

Letter To The Editor ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase

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Efficacy and safety of HIF prolyl-hydroxylase inhibitor vs epoetin and darbepoetin for anemia in chronic kidney disease patients not undergoing dialysis: A network meta-analysis

Pharmacological Research ◽

10.1016/j.phrs.2020.105020 ◽

2020 ◽

Vol 159 ◽

pp. 105020 ◽

Author(s):

Qiyan Zheng ◽

Huisheng Yang ◽

Luying Sun ◽

Ruojun Wei ◽

Xinwen Fu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Meta Analysis ◽

Prolyl Hydroxylase ◽

Efficacy And Safety ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase

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Zinc Inhibits HIF-Prolyl Hydroxylase Inhibitor-Aggravated VSMC Calcification Induced by High Phosphate

Frontiers in Physiology ◽

10.3389/fphys.2019.01584 ◽

2020 ◽

Vol 10 ◽

Author(s):

Annamária Nagy ◽

Dávid Pethő ◽

Tamás Gáll ◽

Erzsébet Zavaczki ◽

Mónika Nyitrai ◽

...

Keyword(s):

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor ◽

Hif Prolyl Hydroxylase ◽

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Short-term treatment with a novel HIF-prolyl hydroxylase inhibitor (GSK1278863) failed to improve measures of performance in subjects with claudication-limited peripheral artery disease

Vascular Medicine ◽

10.1177/1358863x14557151 ◽

2014 ◽

Vol 19 (6) ◽

pp. 473-482 ◽

Author(s):

Eric Olson ◽

Laura Demopoulos ◽

Thomas F Haws ◽

Erding Hu ◽

Zixing Fang ◽

...

Keyword(s):

Peripheral Artery Disease ◽

Term Treatment ◽

Prolyl Hydroxylase ◽

Peripheral Artery ◽

Short Term Treatment ◽

Prolyl Hydroxylase Inhibitor ◽

Artery Disease ◽

Hif Prolyl Hydroxylase ◽

Measures Of Performance

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