scholarly journals E2F transcription factor 1 (E2F1) enhances the proliferation, invasion and EMT of trophoblast cells by binding to Zinc Finger E-Box Binding Homeobox 1 (ZEB1)

Bioengineered ◽  
2022 ◽  
Vol 13 (2) ◽  
pp. 2360-2370
Author(s):  
Han Gong ◽  
Fan Lu ◽  
Xiaoling Zeng ◽  
Qing Bai
Keyword(s):  
Transcription Factor ◽  
Zinc Finger ◽  
Trophoblast Cells ◽  
E Box ◽  
E2f Transcription Factor ◽  
Transcription Factor 1

scholarly journals E2F transcription factor-1 regulates oxidative metabolism

2011 ◽  
Vol 13 (9) ◽  
pp. 1146-1152 ◽  
Author(s):  
Emilie Blanchet ◽  
Jean-Sébastien Annicotte ◽  
Sylviane Lagarrigue ◽  
Victor Aguilar ◽  
Cyrielle Clapé ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Oxidative Metabolism ◽  
E2f Transcription Factor ◽  
Transcription Factor 1

scholarly journals Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Bynthia M. Anose ◽  
Michel M. Sanders
Keyword(s):  
Prostate Cancer ◽  
Transcription Factor ◽  
Signaling Pathways ◽  
Zinc Finger ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Prostate Cancer Cell Line ◽  
Homeodomain Proteins ◽  
Cell Metastasis ◽  
E Box

The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal transitions (EMTs). ZEB1 (also known as δEF1, zfhx1a, TCF8, and Zfhep) plays a key role in regulating such diverse processes as T-cell development, skeletal patterning, reproduction, and cancer cell metastasis. However, the factors that regulate its expression and consequently the signaling pathways in which ZEB1 participates are poorly defined. Because it is induced by estrogen and progesterone and is high in prostate cancer, we investigated whethertcf8, which encodes ZEB1, is regulated by androgen. Data herein demonstrate thattcf8is induced by dihydrotestosterone (DHT) in the human PC-3/AR prostate cancer cell line and that this induction is mediated by two androgen response elements (AREs). These results demonstrate that ZEB1 is an intermediary in androgen signaling pathways.

scholarly journals MicroRNA-485-5p inhibits glioblastoma progression by suppressing E2F transcription factor 1 under cisplatin treatment

Bioengineered ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 8020-8030
Author(s):  
Conggang Huang ◽  
Lan Ma ◽  
Faliang Duan ◽  
Ruixue Li ◽  
Yanguo Zhang ◽  
...  
Keyword(s):  
Transcription Factor ◽  
E2f Transcription Factor ◽  
Transcription Factor 1
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