Precision medicine for the treatment of sepsis: recent advances and future prospects

2019 ◽  
Vol 4 (4) ◽  
pp. 205-213 ◽  
Author(s):  
Pedro Palma ◽  
Jordi Rello
ChemNanoMat ◽  
2021 ◽  
Author(s):  
Yan Zhou ◽  
Dongfang Dai ◽  
Yu Gao ◽  
Zhengdong Zhang ◽  
Nan Sun ◽  
...  

2008 ◽  
Vol 5 (5) ◽  
pp. 671-680 ◽  
Author(s):  
Thomas Degenkolb ◽  
Hans von Döhren ◽  
Kristian Fog Nielsen ◽  
Gary J. Samuels ◽  
Hans Brückner

2016 ◽  
Vol 13 (3) ◽  
pp. 297-308 ◽  
Author(s):  
Yashwanth Subbannayya ◽  
Sneha M. Pinto ◽  
Harsha Gowda ◽  
T. S. Keshava Prasad

2018 ◽  
Vol 2 (5) ◽  
pp. 295-300
Author(s):  
Joan E. Adamo ◽  
Robert V. Bienvenu ◽  
F. Owen Fields ◽  
Soma Ghosh ◽  
Christina M. Jones ◽  
...  

Building on the recent advances in next-generation sequencing, the integration of genomics, proteomics, metabolomics, and other approaches hold tremendous promise for precision medicine. The approval and adoption of these rapidly advancing technologies and methods presents several regulatory science considerations that need to be addressed. To better understand and address these regulatory science issues, a Clinical and Translational Science Award Working Group convened the Regulatory Science to Advance Precision Medicine Forum. The Forum identified an initial set of regulatory science gaps. The final set of key findings and recommendations provided here address issues related to the lack of standardization of complex tests, preclinical issues, establishing clinical validity and utility, pharmacogenomics considerations, and knowledge gaps.


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