DETERMINATION OF FLUOROQUINOLONE ANTIBACTERIALS IN PHARMACEUTICAL FORMULATIONS BY CAPILLARY ELECTROPHORESIS

1999 ◽  
Vol 22 (2) ◽  
pp. 281-296 ◽  
Author(s):  
Shao-Wen Sun ◽  
An-Cheng Wu
Keyword(s):  
Capillary Electrophoresis ◽  
Pharmaceutical Formulations

Determination of Ofloxacin Enantiomers in Pharmaceutical Formulations by Capillary Electrophoresis

2007 ◽  
Vol 31 (3) ◽  
pp. 348-360 ◽  
Author(s):  
Abdalla A. Elbashir ◽  
Bahruddin Saad ◽  
Abdussalam Salhin Mohamed Ali ◽  
Muhammad Idiris Saleh ◽  
Hassan Y. Aboul‐Enein
Keyword(s):  
Capillary Electrophoresis ◽  
Pharmaceutical Formulations ◽  
Ofloxacin Enantiomers

Determination of phenothiazines in pharmaceutical formulations and human urine using capillary electrophoresis with chemiluminescence detection

2006 ◽  
Vol 27 (12) ◽  
pp. 2348-2359 ◽  
Author(s):  
Francisco J. Lara ◽  
Ana M. García-Campaña ◽  
Laura Gámiz-Gracia ◽  
Juan M. Bosque-Sendra ◽  
Fermín Alés-Barrero
Keyword(s):  
Capillary Electrophoresis ◽  
Human Urine ◽  
Pharmaceutical Formulations ◽  
Chemiluminescence Detection

Enantioseparation and Determination of Sibutramine in Pharmaceutical Formulations by Capillary Electrophoresis

2010 ◽  
Vol 31 (6) ◽  
pp. 1496-1500 ◽  
Author(s):  
Hongmei Zhu ◽  
Enqi Wu ◽  
Jianbo Chen ◽  
Chuvan Men ◽  
Yu-Seon Jang ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Pharmaceutical Formulations

Capillary Electrophoresis Methods for the Determination of Tramadol: A Review

2019 ◽  
Vol 25 (4) ◽  
pp. 278-286
Author(s):  
Anita Sarkany ◽  
Gabriel Hancu ◽  
Claudiu Drăguț ◽  
Adriana Modroiu ◽  
Enikő Barabás-Hajdu
Keyword(s):  
Capillary Electrophoresis ◽  
Opioid Analgesic ◽  
Cost Effective ◽  
Pharmaceutical Formulations ◽  
Racemic Mixture ◽  
Effective Solution ◽  
Complex Mechanism ◽  
Biological Matrices ◽  
Opiate Agonist

Tramadol is a widely used opioid analgesic frequently prescribed for treatment of moderate to severe, acute and chronic pain. It has a complex mechanism of action, acting both as a central opiate agonist and as a norepinephrine and serotonin reuptake inhibitor. It is a chiral substance, having two chiral centers in its structure and it is used in therapy as a racemic mixture of two of its enantiomers, (S,S)-tramadol and (R,R)-tramadol. In the last 25 years, several analytical procedures have been published in the literature for the achiral and chiral determination of tramadol from pharmaceutical formulations and biological matrices. Among these methods, capillary electrophoresis techniques have proved to be an efficient, reliable and cost-effective solution. The purpose of the present review is to provide a systematic survey to present and discuss the electrodriven methods available in the literature for the achiral and chiral analysis of tramadol.

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