A MILD, ONE-POT METHOD FOR THE CONVERSION OF CARBOXYLIC ACIDS INTO THE CORRESPONDING WEINREB AMIDES

2001 ◽  
Vol 31 (13) ◽  
pp. 2011-2019 ◽  
Author(s):  
Martin Banwell ◽  
Jason Smith
Keyword(s):  
Carboxylic Acids ◽  
One Pot ◽  
Weinreb Amides

One-Pot Transition-Metal-Free Synthesis of Weinreb Amides Directly from Carboxylic Acids

Synthesis ◽  
2013 ◽  
Vol 46 (03) ◽  
pp. 320-330 ◽  
Author(s):  
Danfeng Huang ◽  
Yulai Hu ◽  
Teng Niu ◽  
Ke-Hu Wang ◽  
Changming Xu ◽  
...  
Keyword(s):  
Transition Metal ◽  
Carboxylic Acids ◽  
One Pot ◽  
Metal Free ◽  
Weinreb Amides

ChemInform Abstract: One-Pot Transition-Metal-Free Synthesis of Weinreb Amides Directly from Carboxylic Acids.

ChemInform ◽  
2014 ◽  
Vol 45 (29) ◽  
pp. no-no
Author(s):  
Teng Niu ◽  
Ke-Hu Wang ◽  
Danfeng Huang ◽  
Changming Xu ◽  
Yingpeng Su ◽  
...  
Keyword(s):  
Transition Metal ◽  
Carboxylic Acids ◽  
One Pot ◽  
Metal Free ◽  
Weinreb Amides

Synthesis of 3-(Cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic Acids Via an Efficient Three-component Condensation Reaction between Cyclohexylisocyanide and 2-Aminopyridine-3-carboxylic Acid in the Presence of Aromatic Aldehyde

2018 ◽  
Vol 21 (4) ◽  
pp. 298-301 ◽  
Author(s):  
Ghasem Marandi
Keyword(s):  
Biological Sciences ◽  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
High Performance ◽  
Condensation Reaction ◽  
Aromatic Aldehydes ◽  
New Materials ◽  
One Pot ◽  
High Yields ◽  
Benzaldehyde Derivatives

Aim and Objective: The reaction of cyclohexylisocyanide and 2-aminopyridine-3- carboxylic acid in the presence of benzaldehyde derivatives in ethanol led to 3-(cyclohexylamino)-2- arylimidazo[1,2-a]pyridine-8-carboxylic acids in high yields. In a three component condensation reaction, isocyanide reacts with 2-aminopyridine-3-carboxylic acid and aromatic aldehydes without any prior activation. Material and Methods: The synthesized products have stable structures which have been characterized by IR, 1H, 13C and Mass spectroscopy as well as CHN-O analysis. Results: In continuation of our attempts to develop simple one-pot routes for the synthesis of 3- (cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids, aromatic aldehydes with divers substituted show a high performance. Conclusion: In conclusion, this study introduces the art of combinatorial chemistry using a simple one-pot procedure for the synthesis of new materials which are interesting compounds in medicinal and biological sciences.

Direct One-Pot Synthesis of α-Siloxy-Weinreb Amides from Aldehydes

2007 ◽  
Vol 72 (25) ◽  
pp. 9850-9853 ◽  
Author(s):  
Hisao Nemoto ◽  
Rujian Ma ◽  
Hideki Moriguchi ◽  
Tomoyuki Kawamura ◽  
Masaki Kamiya ◽  
...  
Keyword(s):  
One Pot ◽  
Weinreb Amides ◽  
One Pot Synthesis

Mild one-pot conversion of carboxylic acids to amides or esters with Ph3P/trichloroisocyanuric acid

2005 ◽  
Vol 46 (35) ◽  
pp. 5945-5947 ◽  
Author(s):  
Rogério da C. Rodrigues ◽  
Igor M.A. Barros ◽  
Edson L.S. Lima
Keyword(s):  
Carboxylic Acids ◽  
One Pot ◽  
Trichloroisocyanuric Acid

Amides in One Pot from Carboxylic Acids and Amines via Sulfinylamides

2014 ◽  
Vol 16 (2) ◽  
pp. 604-607 ◽  
Author(s):  
Jianfei Bai ◽  
Bartosz K. Zambroń ◽  
Pierre Vogel
Keyword(s):  
Carboxylic Acids ◽  
One Pot
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