scholarly journals Herpes Simplex Virus (HSV) Type 2 Glycoprotein D Subunit Vaccines and Protection against Genital HSV‐1 or HSV‐2 Disease in Guinea Pigs

2003 ◽  
Vol 187 (4) ◽  
pp. 542-549 ◽  
Author(s):  
Nigel Bourne ◽  
Fernando J. Bravo ◽  
Myriam Francotte ◽  
David I. Bernstein ◽  
Martin G. Myers ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Guinea Pigs ◽  
Glycoprotein D ◽  
Subunit Vaccines ◽  
Simplex Virus ◽  
D Subunit ◽  
Hsv 1

scholarly journals Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

Virology ◽  
2019 ◽  
Vol 526 ◽  
pp. 180-188 ◽  
Author(s):  
Nigel Bourne ◽  
Brianne N. Banasik ◽  
Clarice L. Perry ◽  
Aaron L. Miller ◽  
Mellodee White ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Guinea Pigs ◽  
Simplex Virus

Typing of Clinical Herpes Simplex Virus Type 1 and Type 2 Isolates with Monoclonal Antibodies

1999 ◽  
Vol 37 (8) ◽  
pp. 2717-2718 ◽  
Author(s):  
Jan-Åke Liljeqvist ◽  
Bo Svennerholm ◽  
Tomas Bergström
Keyword(s):  
Monoclonal Antibody ◽  
Monoclonal Antibodies ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Glycoprotein C ◽  
Glycoprotein G ◽  
Simplex Virus ◽  
Hsv 1

The purpose of this study was to evaluate the performance of a herpes simplex virus (HSV) type 1-specific anti-glycoprotein C-1 monoclonal antibody (MAb) and a type 2-specific anti-glycoprotein G-2 MAb for typing of 2,400 clinical HSV-1 isolates and 2,400 clinical HSV-2 isolates, respectively, using an enzyme immunoassay. The anti-HSV-1 MAb showed sensitivity and specificity of 100%, and the anti-HSV-2 MAb showed a sensitivity of 99.46% and 100% specificity, indicating that these MAbs are suitable for typing of clinical HSV isolates.

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