scholarly journals Provirus Load in Breast Milk and Risk of Mother‐to‐Child Transmission of Human T Lymphotropic Virus Type I

2004 ◽  
Vol 190 (7) ◽  
pp. 1275-1278 ◽  
Author(s):  
Hong‐Chuan Li ◽  
Robert J. Biggar ◽  
Wendell J. Miley ◽  
Elizabeth M. Maloney ◽  
Beverley Cranston ◽  
...  



1993 ◽  
Vol 53 (4) ◽  
pp. 597-600 ◽  
Author(s):  
Kohji Ueda ◽  
Koichi Kusuhara ◽  
Ken Tokugawa ◽  
Chiaki Miyazaki ◽  
Kenji Okada ◽  
...  


2004 ◽  
Vol 70 (2) ◽  
pp. 158-163 ◽  
Author(s):  
KENICHIRO KASHIWAGI ◽  
HISASHI NAKASHIMA ◽  
NAOKO KINUKAWA ◽  
JUN HAYASHI ◽  
NORIHIKO KUBO ◽  
...  


1986 ◽  
Vol 20 (3) ◽  
pp. 253-260 ◽  
Author(s):  
Hidenori Sugiyama ◽  
Hiroshi Doi ◽  
Kyoko Yamaguchi ◽  
Yoshiro Tsuji ◽  
Tsutomu Miyamoto ◽  
...  


1991 ◽  
Vol 49 (5) ◽  
pp. 673-677 ◽  
Author(s):  
Kazuo Takahashi ◽  
Toshiro Takezaki ◽  
Toshitaka Oki ◽  
Kiyoshi Kawakami ◽  
Shinji Yashiki ◽  
...  


1993 ◽  
Vol 168 (3) ◽  
pp. 586-591 ◽  
Author(s):  
R. B. Lal ◽  
R. A. Gongora-Biachi ◽  
D. Pardi ◽  
W. M. Switzer ◽  
I. Goldman ◽  
...  


1995 ◽  
Vol 127 (6) ◽  
pp. 924-928 ◽  
Author(s):  
Russell B. Van Dyke ◽  
Walid Heneine ◽  
Margarita E. Perrin ◽  
Donna Rudolph ◽  
Elizabeth Starszak ◽  
...  


PEDIATRICS ◽  
1990 ◽  
Vol 86 (1) ◽  
pp. 11-17
Author(s):  
Yoshiro Tsuji ◽  
Hiroshi Doi ◽  
Tooru Yamabe ◽  
Tadayuki Ishimaru ◽  
Tsutomu Miyamoto ◽  
...  

Human T-cell lymphotropic virus type I (HTLV-I), an etiologic human retrovirus of adult T-cell leukemia/lymphoma (ATLL), causes approximately 60 new cases of ATLL each year in Nagasaki Prefecture; essentially all cases are fatal, and they account for approximately 0.5% of total deaths in the area. The estimated life risk for an HTLV-I carrier to develop ATLL is approximately 5%. The major transmission pathway of HTLV-I peculiarly endemic in the Nagasaki Prefecture was studied. The prevalence of HTLV-I infection in children of carrier mothers (21%) was significantly higher than that in children in the general population in the area (1%), and more than 85% of mothers of carrier children were carriers. The breast milk of carrier mothers contained HTLV-I-infected cells and was infectious for marmoset via oral administration. A retrospective survey of children of carrier mothers showed that the prevalence of carrier children of carrier mothers was 17 (39%) of 44 and 0 (0%) of 10 when they were given breast milk only or formula only, respectively. These data provide a powerful basis for devising an intervention measure to block the endemic cycle of HTLV-I; ie, if carrier mothers refrain from breast-feeding, the incidence of ATLL will be significantly reduced some 50 years later.



1992 ◽  
Vol 21 (5) ◽  
pp. 989-994 ◽  
Author(s):  
MIKI HIRATA ◽  
JUN HAYASHI ◽  
AKINORI NOGUCHI ◽  
KOYA NAKASHIMA ◽  
WATARU KAJIYAMA ◽  
...  


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