A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay

2016 ◽  
Vol 14 (1) ◽  
pp. 39-49 ◽  
Author(s):  
Mohammed A. Kashem ◽  
Charles A. Kennedy ◽  
Kylie E. Fogarty ◽  
Janice R. Dimock ◽  
Yunlong Zhang ◽  
...  
Keyword(s):  
High Throughput ◽  
Enzyme Assay ◽  
Sphingosine Kinase ◽  
Free Enzyme ◽  
Yeast Cells ◽  
Genetic Complementation ◽  
Sphingosine Kinase 1 ◽  
Selective Inhibitors ◽  
Complementation Assay ◽  
A Cell

scholarly journals Synthesis of selective inhibitors of sphingosine kinase 1

2013 ◽  
Vol 49 (21) ◽  
pp. 2136 ◽  
Author(s):  
Dong Jae Baek ◽  
Neil MacRitchie ◽  
Nigel J. Pyne ◽  
Susan Pyne ◽  
Robert Bittman
Keyword(s):  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Selective Inhibitors

ChemInform Abstract: Synthesis of Selective Inhibitors of Sphingosine Kinase 1.

ChemInform ◽  
2013 ◽  
Vol 44 (25) ◽  
pp. no-no
Author(s):  
Dong Jae Baek ◽  
Neil MacRitchie ◽  
Nigel J. Pyne ◽  
Susan Pyne ◽  
Robert Bittman
Keyword(s):  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Selective Inhibitors

scholarly journals Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity

2017 ◽  
Vol 60 (9) ◽  
pp. 3933-3957 ◽  
Author(s):  
Elizabeth S. Childress ◽  
Yugesh Kharel ◽  
Anne M. Brown ◽  
David R. Bevan ◽  
Kevin R. Lynch ◽  
...  
Keyword(s):  
Sphingosine Kinase ◽  
Sphingosine Kinase 1 ◽  
Selective Inhibitors ◽  
Design Synthesis ◽  
Sphingosine Kinase 2

Sphingosine kinase 1 is a relevant molecular target in gastric cancer

2011 ◽  
Vol 22 (3) ◽  
pp. 245-252 ◽  
Author(s):  
Thorsten Fuereder ◽  
Doris Hoeflmayer ◽  
Agnes Jaeger-Lansky ◽  
Doris Rasin-Streden ◽  
Sabine Strommer ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Sphingosine Kinase ◽  
Molecular Target ◽  
Sphingosine Kinase 1
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