Increased Seroreactivity to Human T Cell Lymphoma/Leukemia Virus-Related Endogenous Sequence-1 Gag Peptides in Patients with Human T Cell Lymphoma/Leukemia Virus Myelopathy

2015 ◽  
Vol 31 (2) ◽  
pp. 242-249 ◽  
Author(s):  
Raisa Perzova ◽  
Elliot Graziano ◽  
Swathi Sanghi ◽  
Caitlin Welch ◽  
Patricia Benz ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
Leukemia Virus ◽  
T Cell Lymphoma ◽  
Human T Cell ◽  
Endogenous Sequence

scholarly journals Seroprevalence of human T-cell lymphoma/leukemia virus type-1 (HTLV-1) antibodies among blood donors at Enugu, Nigeria

2015 ◽  
pp. 31 ◽  
Author(s):  
Robinson Onoh ◽  
Augustine Okoye ◽  
Godswill Obed Ibegbulam ◽  
Ngozi Immaculata Ugwu ◽  
Chukwudi Siemon Anigbo ◽  
...  
Keyword(s):  
T Cell ◽  
Virus Type ◽  
Blood Donors ◽  
Cell Lymphoma ◽  
Leukemia Virus ◽  
T Cell Lymphoma ◽  
Human T Cell

scholarly journals Natural antibodies to the human T cell lymphoma virus in patients with cutaneous T cell lymphomas.

1981 ◽  
Vol 154 (2) ◽  
pp. 333-346 ◽  
Author(s):  
L E Posner ◽  
M Robert-Guroff ◽  
V S Kalyanaraman ◽  
B J Poiesz ◽  
F W Ruscetti ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
Solid Phase ◽  
Leukemia Virus ◽  
Calf Serum ◽  
Natural Antibodies ◽  
T Cell Lymphoma ◽  
T Cell Lymphomas ◽  
Human T Cell ◽  
Core Proteins

Sera from patients with cutaneous T cell lymphoma and leukemia were screened for the presence of natural antibody to the human T cell lymphoma (leukemia) virus, HTLVCR, using a solid-phase radioimmunoassay. Sera from two patients, including patient CR, from whose cultured T lymphoblastic cell line (HUT102), the retrovirus HTLVCR was isolated, reacted specifically with proteins of HTLVCR. Serum from patient CR also reacted specifically with proteins of HTLVMB, an independent but highly related retroviral isolate from a patient with Sezary T cell leukemia. The specificity for HTLVCR proteins was demonstrated by solid-phase immunocompetition assays and competition radioimmunoprecipitation assays. Analysis of radioimmunoprecipitates indicated that the natural antibodies were directed against HTLVCR core proteins with molecular weights of 24,000 and 19,000 (p24 and p19). Whereas the serum reactivities for HTLVCR proteins were shown to be highly specific, additional reactivities seen against proteins of animal retroviruses including GaLV, SSV, FeLV, and BaEV were clearly shown not to be viral specific but rather were due to reactivity with cellular antigens contaminating the viral preparations or with related antigens present in fetal calf serum. These results demonstrating natural antibodies to HTLVCR provide the first evidence for a specific antibody response to a retrovirus in humans.

Antibodies to the Human T-Cell Lymphoma/Leukemia Virus Type I in Dutch Haemophiliacs

Vox Sanguinis ◽  
1986 ◽  
Vol 50 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Jaap Goudsmit ◽  
Frank Miedemca ◽  
Cees Breederveld ◽  
Fokke Terpstra ◽  
Marijke Roos ◽  
...  
Keyword(s):  
T Cell ◽  
Virus Type ◽  
Cell Lymphoma ◽  
Leukemia Virus ◽  
T Cell Lymphoma ◽  
Type I ◽  
Human T Cell

scholarly journals Slithering Through the Bone Marrow: Loiasis in a Patient With Human T-Cell Leukemia Virus-1-Associated Adult T-Cell Lymphoma

2020 ◽  
Vol 7 (12) ◽  
Author(s):  
Carl Boodman ◽  
Daniel Marko ◽  
Yoav Keynan
Keyword(s):  
Bone Marrow ◽  
T Cell ◽  
Cell Lymphoma ◽  
Leukemia Virus ◽  
T Cell Lymphoma ◽  
Cell Leukemia ◽  
Loa Loa ◽  
Human T Cell ◽  
T Cell Leukemia Virus

Abstract Loiasis is a filarial disease endemic to areas of Central and West Africa. We present a case of Loa loa microfilaremia in a patient with HTLV-1-related adult T-cell lymphoma. This case may suggest the possible role of cellular immunity in controlling microfilaria burden.

scholarly journals Full-Genome Characterization of Simian T-Cell Leukemia Virus Type 1 Subtype b from a Wild-Born Captive Gorilla gorilla gorilla with T-Cell Lymphoma

2017 ◽  
Vol 5 (43) ◽  
Author(s):  
Ahidjo Ayouba ◽  
Annelies Michem ◽  
Martine Peeters ◽  
Francis Vercammen
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
Leukemia Virus ◽  
Gorilla Gorilla ◽  
T Cell Lymphoma ◽  
Cell Leukemia Virus Type ◽  
B Genome ◽  
Subtype B ◽  
Human T Cell ◽  
T Cell Leukemia Virus

ABSTRACT There are four lineages of primate T-cell lymphocytic viruses (human T-cell lymphocytic virus [HTLV]/simian T-cell lymphocytic virus [STLV]), which are further divided into subtypes. To date, there is only one full-length HTLV-1 subtype b genome available. Here, we report the genome of a new STLV-1 subtype b from a 43-year-old male gorilla with T-cell lymphoma.

Sign in / Sign up

Export Citation Format

Share Document