Experimental Efficacy of Mycophenolate Mofetil Implant on High-Risk Corneal Allograft Rejection and Its Biocompatibility in the Anterior Chamber of Rabbits

2012 ◽  
Vol 28 (6) ◽  
pp. 609-617 ◽  
Author(s):  
Meng Xin ◽  
Ting Wang ◽  
Weiyun Shi ◽  
Xianggen Wu
1995 ◽  
Vol 59 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Amy B. Hahn ◽  
Gary N. Foulks ◽  
Cheryl Enger ◽  
Nancy Fink ◽  
Walter J. Stark ◽  
...  

2018 ◽  
Vol 59 (10) ◽  
pp. 3911 ◽  
Author(s):  
Han Wang ◽  
Qingqing Zhao ◽  
Dan Luo ◽  
Yizhou Yin ◽  
Ting Li ◽  
...  

2020 ◽  
Vol 20 (12) ◽  
pp. 3354-3366
Author(s):  
Chao Wei ◽  
Li Ma ◽  
Hao Chi ◽  
Lin Li ◽  
Sai Zhang ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Afsaneh Amouzegar ◽  
Sunil K. Chauhan

Corneal transplantation is among the most prevalent and successful forms of solid tissue transplantation in humans. Failure of corneal allograft is mainly due to immune-mediated destruction of the graft, a complex and highly coordinated process that involves elaborate interactions between cells of innate and adaptive immunity. The migration of immune cells to regional lymphoid tissues and to the site of graft plays a central role in the immunopathogenesis of graft rejection. Intricate interactions between adhesion molecules and their counter receptors on immune cells in conjunction with tissue-specific chemokines guide the trafficking of these cells to the draining lymph nodes and ultimately to the site of graft. In this review, we discuss the cascade of chemokines and adhesion molecules that mediate the trafficking of effector and regulatory T cells during corneal allograft rejection.


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