A Morphological and Molecular Characterization of the Spinal Cord after Ventral Root Avulsion or Distal Peripheral Nerve Axotomy Injuries in Adult Rats

2017 ◽  
Vol 34 (3) ◽  
pp. 652-660 ◽  
Author(s):  
Rebecca Wiberg ◽  
Paul J. Kingham ◽  
Liudmila N. Novikova
Keyword(s):  
Spinal Cord ◽  
Peripheral Nerve ◽  
Molecular Characterization ◽  
Ventral Root ◽  
Root Avulsion ◽  
Adult Rats ◽  
Ventral Root Avulsion ◽  
Morphological And Molecular Characterization

scholarly journals Delayed Spinal Cord–Brachial Plexus Reconnection after C7 Ventral Root Avulsion: The Effect of Reinnervating Motoneurons Rescued by Riluzole Treatment

2017 ◽  
Vol 34 (15) ◽  
pp. 2364-2374 ◽  
Author(s):  
Balázs Gloviczki ◽  
Dénes G. Török ◽  
Gábor Márton ◽  
László Gál ◽  
Tamás Bodzay ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Brachial Plexus ◽  
Ventral Root ◽  
Root Avulsion ◽  
Ventral Root Avulsion

Ventral root avulsion versus transection at the cervical 7 level of the cat spinal cord

1993 ◽  
Vol 5 (4) ◽  
pp. 291-302
Author(s):  
C.F.E. Hoffmann ◽  
E. Marani ◽  
A.B. Oestreicher ◽  
R.T.W.M. Thomeer
Keyword(s):  
Spinal Cord ◽  
Ventral Root ◽  
Root Avulsion ◽  
Ventral Root Avulsion

Ventral root avulsion leads to downregulation of glur2 subunit in spinal motoneurons in adult rats

Neuroscience ◽  
2003 ◽  
Vol 117 (1) ◽  
pp. 139-146 ◽  
Author(s):  
I Nagano ◽  
T Murakami ◽  
M Shiote ◽  
K Abe ◽  
Y Itoyama
Keyword(s):  
Ventral Root ◽  
Root Avulsion ◽  
Spinal Motoneurons ◽  
Adult Rats ◽  
Ventral Root Avulsion

scholarly journals Transgenic human embryonic stem cells overexpressing FGF2 stimulate neuroprotection following spinal cord ventral root avulsion

2017 ◽  
Vol 294 ◽  
pp. 45-57 ◽  
Author(s):  
Marta Rocha Araújo ◽  
Sergiy Kyrylenko ◽  
Aline Barroso Spejo ◽  
Mateus Vidigal Castro ◽  
Rui Seabra Ferreira Junior ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Ventral Root ◽  
Root Avulsion ◽  
Ventral Root Avulsion

scholarly journals Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Thiago B. Ribeiro ◽  
Adriana S. S. Duarte ◽  
Ana Leda F. Longhini ◽  
Fernando Pradella ◽  
Alessandro S. Farias ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells ◽  
Ventral Root ◽  
Root Avulsion ◽  
Ventral Root Avulsion

Experimental Studies on Surgical Treatment of Avulsed Spinal Nerve Roots in Brachial Plexus Injury

1991 ◽  
Vol 16 (5) ◽  
pp. 477-482 ◽  
Author(s):  
T. CARLSTEDT
Keyword(s):  
Spinal Cord ◽  
Surgical Treatment ◽  
Brachial Plexus ◽  
Experimental Studies ◽  
Sensory Nerve ◽  
Spinal Nerve ◽  
Ventral Root ◽  
Root Avulsion ◽  
Nerve Fibres ◽  
Ventral Root Avulsion

This review summarises studies aiming at a surgical treatment of spinal nerve root avulsions from the spinal cord in brachial plexus lesions. After dorsal root injury, regrowth of nerve fibres into the spinal cord occurs only in the immature animal. After ventral root avulsion and subsequent implantation into the spinal cord, neuroanatomical and neurophysiological data show that motoneurons are capable of producing new axons which enter the implanted root. Intra-neuronal physiological experiments demonstrate that new axons can conduct action potentials and elicit muscle responses. The neurons are reconnected in segmental spinal cord activity and respond to impulses in sensory nerve fibres. In primate experiments, implantation of avulsed ventral roots in the brachial plexus resulted in functional restitution. These studies indicate the possibility of surgical treatment of ventral root avulsion injuries in brachial plexus lesions in humans.

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