Bone Marrow Stromal Cells in a Liquid Fibrin Matrix Improve the Healing Process of Patellar Tendon Window Defects

2009 ◽  
Vol 15 (5) ◽  
pp. 1019-1030 ◽  
Author(s):  
Stefan Hankemeier ◽  
Christof Hurschler ◽  
Johannes Zeichen ◽  
Martijn van Griensven ◽  
Brian Miller ◽  
...  
2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Preethi Balasubramanian ◽  
Rainer Detsch ◽  
Leticia Esteban-Tejeda ◽  
Alina Grünewald ◽  
José S. Moya ◽  
...  

AbstractThis study evaluated the influence of ionic dissolution products of a novel Ca-enriched silicate bioactive glass compared to commercial available hydroxyapaptite samples (Endobonr) on cell activity and vascular endothelial growth factor (VEGF) release in vitro. Bone marrow stromal cells (ST-2) were cultivated with the supernatant of granules of different sizes and at different concentrations (0-1 wt/vol % of granules) for 48 h. In addition to in vitro studies, Ca-ion release from all as cell morphology observation revealed no cytotoxic effect of the released products from all tested materials. It was found that supernatants from granules in concentrations of 1 wt/vol %enhanced the VEGF release from ST2 cells, which is important as a marker of the vascularisation ability of the glass during the bone healing process.


2013 ◽  
Author(s):  
Sylvia Thiele ◽  
Alexander Rauch ◽  
Jan P Tuckermann ◽  
Lorenz C Hofbauer ◽  
Martina Rauner

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