Quality Control of Multichannel Hematology Analyzers: Evaluation of Bull’s Algorithm

1985 ◽  
Vol 83 (3) ◽  
pp. 337-345 ◽  
Author(s):  
George S. Cembrowski ◽  
James O. Westgard
1992 ◽  
Vol 97 (5) ◽  
pp. 645-651
Author(s):  
Veli Kairisto ◽  
Timo Kouri ◽  
Allan Rajamäki ◽  
Arja Virtanen ◽  
Esa Uusipaikka ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yu Aruga ◽  
Chiaki Ikeda ◽  
Arisa Hanai ◽  
Sakiko Yoshimura ◽  
Momoko Kito ◽  
...  

AbstractThe chylous turbidity of blood samples is one of the causes of false-high hemoglobin (Hgb) concentration measurements by the colorimetric method, which has been widely applied in hematology analyzers. In such cases, additional manual procedures are required to correct Hgb concentrations. We therefore examined the effectiveness of an optical method for measuring Hgb concentrations in samples with chylous turbidity using Hgb-O in the reticulocyte channel equipped in XN-series analyzers (Sysmex, Kobe, Japan). Hgb-O showed excellent basic performance, including linear correlation and invariability with sodium lauryl sulfate (SLS)-Hgb detected by the colorimetric method. In the analysis of samples from healthy volunteers supplemented with fat emulsion, chylous turbidity did not affect Hgb-O but SLS-Hgb, which was falsely increased according to the dose of fat emulsion. Actually, SLS-Hgb was falsely elevated in 34 of 40 chylous turbidity 3+ samples. The remaining 6 samples were measured in hematology analyzers where Hgb-O was inconsistent with SLS-Hgb in the internal quality control records. For these samples, the correction factors calculated from the internal quality control records could contribute to providing the corrected Hgb-O value. These findings suggested that the optical method was effective and convenient for accurately evaluating Hgb concentrations in samples with extremely chylous turbidity.


2019 ◽  
Vol 8 (3) ◽  
pp. 40
Author(s):  
M. G. Vershinina ◽  
N. A. Steriopolo ◽  
V. Yu. Ibragimova

1988 ◽  
Vol 89 (2) ◽  
pp. 203-210 ◽  
Author(s):  
George S. Cembrowski ◽  
Ellen S. Lunetzky ◽  
Carol C. Patrick ◽  
Majorie K. Wilson

2003 ◽  
Vol 118 (3) ◽  
pp. 193-196 ◽  
Author(s):  
Jeffrey W McKenna ◽  
Terry F Pechacek ◽  
Donna F Stroup

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