SQUIRE: a randomised, multicentre, open-label, phase III study of gemcitabine-cisplatin (GC) plus necitumumab (N) versus GC alone in the first-line treatment of patients (pts) with stage IV squamous non-small cell lung cancer (sq-NSCLC); Subgroup efficacy and safety data for pts with epidermal growth factor receptor (EGFR)-expressing tumours

Annals of Oncology ◽

10.1093/annonc/mdw332.05 ◽

2016 ◽

Vol 27 ◽

pp. iv4

Author(s):

N. Zilembo ◽

L. Giannetta ◽

L. Crinò ◽

A. Bearz ◽

D. Amoroso ◽

...

Keyword(s):

Safety Data ◽

Growth Factor Receptor ◽

Stage Iv ◽

Phase Iii ◽

Small Cell Lung ◽

Open Label Phase ◽

Phase Iii Study ◽

Epidermal Growth

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1320_PR: Subgroup analyses of patients with epidermal growth factor receptor (EGFR)-expressing tumors in SQUIRE: A randomized, multicenter, open-label, phase III study of gemcitabine–cisplatin (GC) plus necitumumab (N) versus GC alone in the first-line treatment of patients (pts) with stage IV squamous non-small cell lung cancer (sq-NSCLC)

Journal of Thoracic Oncology ◽

10.1016/s1556-0864(16)30326-4 ◽

2016 ◽

Vol 11 (4) ◽

pp. S153 ◽

Author(s):

L. Paz-Ares ◽

M.A. Socinski ◽

J. Shahidi ◽

R.R. Hozak ◽

V. Soldatenkova ◽

...

Keyword(s):

Growth Factor Receptor ◽

Stage Iv ◽

Phase Iii ◽

Small Cell Lung ◽

Open Label Phase ◽

Phase Iii Study ◽

Epidermal Growth

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Correlation of EGFR-expression with safety and efficacy outcomes in SQUIRE: a randomized, multicenter, open-label, phase III study of gemcitabine–cisplatin plus necitumumab versus gemcitabine–cisplatin alone in the first-line treatment of patients with stage IV squamous non-small-cell lung cancer

Annals of Oncology ◽

10.1093/annonc/mdw214 ◽

2016 ◽

Vol 27 (8) ◽

pp. 1573-1579 ◽

Author(s):

L. Paz-Ares ◽

M.A. Socinski ◽

J. Shahidi ◽

R.R. Hozak ◽

V. Soldatenkova ◽

...

Keyword(s):

Stage Iv ◽

Phase Iii ◽

Small Cell Lung ◽

Egfr Expression ◽

Open Label Phase ◽

Phase Iii Study ◽

First Line Treatment

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Squire: a Randomized, Multicenter, Open-Label, Phase III Study of Gemcitabine-Cisplatin (Gc) Chemotherapy Plus Necitumumab (Imc-11F8/Ly3012211) Vs Gc Alone in the First-Line Treatment of Patients (Pts) with Stage Iv Squamous Non-Small Cell Lung Cancer (Sq-Nsclc): Update on Key Subgroups

Annals of Oncology ◽

10.1093/annonc/mdu349.11 ◽

2014 ◽

Vol 25 ◽

pp. iv430 ◽

Author(s):

M.A. Socinski ◽

L. Paz-Ares ◽

A.V. Luft ◽

A. Szczesna ◽

T.E. Ciuleanu ◽

...

Keyword(s):

Stage Iv ◽

Phase Iii ◽

Line Treatment ◽

Small Cell Lung ◽

Open Label Phase ◽

Phase Iii Study ◽

First Line Treatment

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A randomized, multicenter, open-label, phase III study of gemcitabine-cisplatin (GC) chemotherapy plus necitumumab (IMC-11F8/LY3012211) versus GC alone in the first-line treatment of patients (pts) with stage IV squamous non-small cell lung cancer (sq-NSCLC).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.8008 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 8008-8008 ◽

Author(s):

Nick Thatcher ◽

Fred R. Hirsch ◽

Aleksandra Szczesna ◽

Tudor-Eliade Ciuleanu ◽

Wojciech Szafranski ◽

...

Keyword(s):

Stage Iv ◽

Phase Iii ◽

Line Treatment ◽

Small Cell Lung ◽

Open Label Phase ◽

Phase Iii Study ◽

First Line Treatment

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Subgroup Analysis of Elderly Patients in Squire: a Randomized, Multicenter, Open-Label, Phase Iii Study of Necitumumab (N) Plus Gemcitabine-Cisplatin (GC) Chemotherapy Versus Gc Alone in First-Line Treatment of Patients (PTS) with Stage Iv Squamous Non-Small Cell Lung Cancer (SQ-NSCLC)

Annals of Oncology ◽

10.1093/annonc/mdv050.07 ◽

2015 ◽

Vol 26 ◽

pp. i29 ◽

Author(s):

N. Thatcher ◽

T.-E. Ciuleanu ◽

R. Ramlau ◽

C. Schumann ◽

L. Paz-Ares ◽

...

Keyword(s):

Stage Iv ◽

Phase Iii ◽

Line Treatment ◽

Small Cell Lung ◽

Open Label Phase ◽

Phase Iii Study ◽

First Line Treatment

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PRONOUNCE: Randomized, Open-Label, Phase III Study of First-Line Pemetrexed + Carboplatin Followed by Maintenance Pemetrexed versus Paclitaxel + Carboplatin + Bevacizumab Followed by Maintenance Bevacizumab in Patients ith Advanced Nonsquamous Non–Small-Cell Lung Cancer

Journal of Thoracic Oncology ◽

10.1097/jto.0000000000000366 ◽

2015 ◽

Vol 10 (1) ◽

pp. 134-142 ◽

Author(s):

Ralph G. Zinner ◽

Coleman K. Obasaju ◽

David R. Spigel ◽

Robert W. Weaver ◽

J. Thaddeus Beck ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Phase Iii ◽

Small Cell Lung ◽

Open Label Phase ◽

Phase Iii Study

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Patient-reported outcomes with first-line durvalumab plus platinum-etoposide versus platinum-etoposide in extensive-stage small-cell lung cancer (CASPIAN): a randomized, controlled, open-label, phase III study

Lung Cancer ◽

10.1016/j.lungcan.2020.09.003 ◽

2020 ◽

Vol 149 ◽

pp. 46-52

Author(s):

Jonathan W. Goldman ◽

Marina Chiara Garassino ◽

Yuanbin Chen ◽

Mustafa Özgüroğlu ◽

Mikhail Dvorkin ◽

...

Keyword(s):

Patient Reported Outcomes ◽

Phase Iii ◽

Small Cell Lung ◽

Randomized Controlled ◽

Patient Reported ◽

Open Label Phase ◽

Phase Iii Study ◽

Extensive Stage

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A Randomized, Open-Label, Phase II Study Comparing Pemetrexed Plus Cisplatin Followed by Maintenance Pemetrexed versus Pemetrexed Alone in Patients with Epidermal Growth Factor Receptor (EGFR)-Mutant Non-small Cell Lung Cancer after Failure of First-Line EGFR Tyrosine Kinase Inhibitor: KCSG-LU12-13

Cancer Research and Treatment ◽

10.4143/crt.2018.324 ◽

2019 ◽

Vol 51 (2) ◽

pp. 718-726

Author(s):

Kwai Han Yoo ◽

Su Jin Lee ◽

Jinhyun Cho ◽

Ki Hyeong Lee ◽

Keon Uk Park ◽

...

Keyword(s):

Kinase Inhibitor ◽

Phase Ii Study ◽

Growth Factor Receptor ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitor ◽

Open Label Phase ◽

Epidermal Growth ◽

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Overall survival (OS) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (Del19/L858R) epidermal growth factor receptor mutations (EGFR mut): Pooled analysis of two large open-label phase III studies (LUX-Lung 3 [LL3] and LUX-Lung 6 [LL6]) comparing afatinib with chemotherapy (CT).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.8004 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 8004-8004 ◽

Author(s):

James Chih-Hsin Yang ◽

Lecia V. Sequist ◽

Martin H. Schuler ◽

Tony Mok ◽

Nobuyuki Yamamoto ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor Receptor ◽

Pooled Analysis ◽

Phase Iii ◽

Small Cell Lung ◽

Open Label Phase ◽

Epidermal Growth ◽

Phase Iii Studies

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Abstract OT2-05-01: FAMILY: A randomized, multicenter, open-label, phase III trial of fulvestrant versus capecitabine as maintenance therapy after first-line combination chemotherapy in patients with hormone receptor-positive, human epidermal growth factor receptor-2 negative metastatic breast cancer

10.1158/1538-7445.sabcs18-ot2-05-01 ◽

2019 ◽

Author(s):

H Yao ◽

W Wu ◽

L Ding ◽

Y Yu ◽

Y Wang ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor Receptor ◽

Metastatic Breast ◽

Phase Iii ◽

Phase Iii Trial ◽

Hormone Receptor Positive ◽

Open Label Phase ◽

Epidermal Growth

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