scholarly journals Clinical and Cardiac Safety of Long-term Levofloxacin in Children Treated for Multidrug-resistant Tuberculosis

2018 ◽  
Vol 67 (11) ◽  
pp. 1777-1780 ◽  
Author(s):  
Anthony J Garcia-Prats ◽  
Heather R Draper ◽  
Heather Finlayson ◽  
Jana Winckler ◽  
André Burger ◽  
...  
2013 ◽  
Vol 17 (suppl_1) ◽  
pp. S44-S44
Author(s):  
Evgeny Medovarov ◽  
A. Pavlunin ◽  
N. Melnikov ◽  
M. Borodachev ◽  
A. Kuznetsova ◽  
...  

Author(s):  
Irina Chernokhaeva ◽  
Maria Pavlova ◽  
Anna Starshinova ◽  
Nadezhda Sapozhnikova ◽  
Liudmila Archakova ◽  
...  

Respiration ◽  
2013 ◽  
Vol 86 (6) ◽  
pp. 472-478 ◽  
Author(s):  
Young Ae Kang ◽  
Song Yee Kim ◽  
Kyung-Wook Jo ◽  
Hee Jin Kim ◽  
Seung-Kyu Park ◽  
...  

Author(s):  
Yiwang Chen ◽  
Lecai Ji ◽  
Qingyun Liu ◽  
Jinli Li ◽  
Chuangyue Hong ◽  
...  

Abstract Tuberculosis heteroresistance, in which only a fraction of the bacteria in a patient with tuberculosis contains drug-resistant mutations, has been a rising concern. However, its origins and prevalence remain elusive. Here, whole-genome sequencing was performed on 83 serial isolates from 31 patients with multidrug-resistant tuberculosis, and heteroresistance was detected in isolates from 21 patients (67.74%). Heteroresistance persisted in the host for long periods, spanning months to years, and was associated with having multiple tubercular lesions. Our findings indicate that heteroresistance is common and persistent in patients with multidrug-resistant tuberculosis and may affect the success of their treatment regimens.


2016 ◽  
Vol 1 (3) ◽  
pp. e000006 ◽  
Author(s):  
Olanrewaju Oladimeji ◽  
Boniface Ayanbekongshie Ushie ◽  
Ekerette Emmanuel Udoh ◽  
Kelechi Elizabeth Oladimeji ◽  
Olusoji Mayowa Ige ◽  
...  

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