Optical tweezers-based immunosensor detects femtomolar concentrations of antigens
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Abstract We used optical tweezers (optical trapping technology) to measure the force required to separate antigen–antibody bonds. Under competitive-binding conditions, we used the force determination to detect and measure protein antigen concentrations as small as 1 fmol/L (10−15 mol/L).
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2019 ◽
Vol 29
(7)
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pp. 1970043
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2010 ◽
Vol 19
(02)
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pp. 371-378
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1997 ◽
Vol 64
(1-3)
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pp. 127-137
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2018 ◽
Vol 29
(7)
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pp. 1808258
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