Septic Shock Due to Pasteurella multocida Subspecies multocida in a Previously Healthy Woman

A 66 years old Caucasian woman with pneumococcal meningitis was treated and discharged after an uncomplicated course. Five months later she was readmitted withfever and right side abdominal pain and diagnosed with pneumococcal spondylodiscitis. One year later she was treated fora severe chest X-ray confirmed left lobar pneumonia. Two years later she was diagnosed with a pneumococcal pneumonia inher left lung with septic shock. An immunedeficiency screen revealed slightly reduced IgA levels, low IgG2 levels, low IgG3 levels and high IgG1 levels. No other immunedefects were identified. She did not respondserologically on vaccination with 13-valentconjugate and 23-valent polysaccharide pneumococcal vaccines. Further evaluations revealed a positive M-component inher blood and a bone marrow biopsy diagnosed her to have monoclonal gammopathy of undetermined significance. To protecther against future life threatening pneumococcal infections she was started on treatment with intravenous immunoglobulin. The case report illustrates the importance of thorough evaluation of patients with unusual infectious disease entities or unusual frequency of infections in individual patients. To optimize prophylactic measures and active treatment options in the individual patient, it is important to identify underlying causes of diseases and immune deficiencies that potentially can lead to life threatening infections. This is illustrated inour case by an undiagnosed monoclonal gammopathy of undetermined significancein an apparently healthy woman with atleast three life threatening documented pneumococcal infections in a two-year period and poor pneumococcal vaccine response

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Septic Shock Secondary to Spontaneous Bacterial Peritonitis Caused by <i>Pasteurella multocida</i>: A Case Report and Review of the Literature

International Journal of Clinical and Experimental Medical Sciences ◽

10.11648/j.ijcems.20210701.11 ◽

2021 ◽

Vol 7 (1) ◽

pp. 1

Author(s):

Bianca Varda ◽

Zaid Ansari ◽

Syed Zaidi ◽

Layth Al-Jashaami

Keyword(s):

Septic Shock ◽

Case Report ◽

Spontaneous Bacterial Peritonitis ◽

Pasteurella Multocida ◽

Review Of The Literature ◽

Bacterial Peritonitis

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Spontaneous Empyema and Overwhelming Septic Shock due to Pasteurella multocida

Scandinavian Journal of Infectious Diseases ◽

10.1080/0036554021000026995 ◽

2003 ◽

Vol 35 (2) ◽

pp. 132-133 ◽

Cited By ~ 7

Author(s):

Kevin B. Laupland ◽

Karen P. Rimmer ◽

Daniel B. Gregson ◽

David W. Megran

Keyword(s):

Septic Shock ◽

Pasteurella Multocida

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Cardiac tamponade and septic shock caused by viral infection in a previously healthy woman

Acta Anaesthesiologica Scandinavica ◽

10.1111/j.1399-6576.2005.00748.x ◽

2005 ◽

Vol 49 (9) ◽

pp. 1384-1386 ◽

Cited By ~ 1

Author(s):

J. J. Laurila ◽

T. I. Ala-Kokko ◽

H. Tuokko ◽

H. Syrjala

Keyword(s):

Septic Shock ◽

Viral Infection ◽

Cardiac Tamponade ◽

Healthy Woman

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Septic shock due to Pasteurella multocida bacteremia: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-015-0643-3 ◽

2015 ◽

Vol 9 (1) ◽

Cited By ~ 8

Author(s):

Niyati Narsana ◽

Faria Farhat

Keyword(s):

Septic Shock ◽

Case Report ◽

Pasteurella Multocida

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Septic shock due toPseudomonas aeruginosa in a previously healthy woman

Intensive Care Medicine ◽

10.1007/bf01701476 ◽

1995 ◽

Vol 21 (3) ◽

pp. 226-228 ◽

Cited By ~ 11

Author(s):

S. Ishihara ◽

M. Takino ◽

Y. Okada ◽

K. Mimura

Keyword(s):

Septic Shock ◽

Healthy Woman

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A Case of Pasteurella Multocida Pneumonia, Bacteremia, and Septic Shock

10.21203/rs.3.rs-315527/v1 ◽

2021 ◽

Author(s):

Wesley Tang ◽

Sulagna Das ◽

James Galbraith

Keyword(s):

Septic Shock ◽

Pasteurella Multocida ◽

Relevant Literature ◽

Domestic Animals ◽

Immunocompetent Patient ◽

Hodgkin's Lymphoma ◽

Human Pathogen ◽

Pulmonary Lesions ◽

History Of ◽

Immunocompromised State

Abstract Pasteurella multocida is a ubiquitous organism found in the oropharynx of healthy domestic animals, especially dogs and cats. It is most known as a human pathogen, reported after animal bite incidents. In atraumatic infections, Pasteurella has been associated with patients in an immunocompromised state, such as those with Hodgkin’s lymphoma, patients with known cirrhosis, or those with preexisting cavitary pulmonary lesions. It is rare to isolate Pasteurella in an immunocompetent patient without known trauma. Here, we present a case of Pasteurella multocida pneumonia, bacteremia, and septic shock in an individual without a history of an animal bite, with a review of relevant literature.

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