Septic shock due toPseudomonas aeruginosa in a previously healthy woman

1995 ◽  
Vol 21 (3) ◽  
pp. 226-228 ◽  
Author(s):  
S. Ishihara ◽  
M. Takino ◽  
Y. Okada ◽  
K. Mimura
Keyword(s):  
Septic Shock ◽  
Healthy Woman

scholarly journals Meningitis, spondylodiscitis, pneumonia and septic shock with Streptococcus pneumoniae in a previously healthy woman with isolated IgG2-, IgG3-, IgA-deficiency and monoclonal gammopathy of undetermined significance

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Shahin Gaini ◽  
David Gudnason ◽  
Bjarni á Steig ◽  
Jenny Jónsdóttir Nielsen
Keyword(s):  
Septic Shock ◽  
Monoclonal Gammopathy ◽  
Left Lung ◽  
Healthy Woman ◽  
Caucasian Woman ◽  
Vaccine Response ◽  
Pneumococcal Infections ◽  
Prophylactic Measures ◽  
Life Threatening ◽  
Undetermined Significance

A 66 years old Caucasian woman with pneumococcal meningitis was treated and discharged after an uncomplicated course. Five months later she was readmitted withfever and right side abdominal pain and diagnosed with pneumococcal spondylodiscitis. One year later she was treated fora severe chest X-ray confirmed left lobar pneumonia. Two years later she was diagnosed with a pneumococcal pneumonia inher left lung with septic shock. An immunedeficiency screen revealed slightly reduced IgA levels, low IgG2 levels, low IgG3 levels and high IgG1 levels. No other immunedefects were identified. She did not respondserologically on vaccination with 13-valentconjugate and 23-valent polysaccharide pneumococcal vaccines. Further evaluations revealed a positive M-component inher blood and a bone marrow biopsy diagnosed her to have monoclonal gammopathy of undetermined significance. To protecther against future life threatening pneumococcal infections she was started on treatment with intravenous immunoglobulin. The case report illustrates the importance of thorough evaluation of patients with unusual infectious disease entities or unusual frequency of infections in individual patients. To optimize prophylactic measures and active treatment options in the individual patient, it is important to identify underlying causes of diseases and immune deficiencies that potentially can lead to life threatening infections. This is illustrated inour case by an undiagnosed monoclonal gammopathy of undetermined significancein an apparently healthy woman with atleast three life threatening documented pneumococcal infections in a two-year period and poor pneumococcal vaccine response

Cardiac tamponade and septic shock caused by viral infection in a previously healthy woman

2005 ◽  
Vol 49 (9) ◽  
pp. 1384-1386 ◽  
Author(s):  
J. J. Laurila ◽  
T. I. Ala-Kokko ◽  
H. Tuokko ◽  
H. Syrjala
Keyword(s):  
Septic Shock ◽  
Viral Infection ◽  
Cardiac Tamponade ◽  
Healthy Woman

Septic Shock Due to Pasteurella multocida Subspecies multocida in a Previously Healthy Woman

1995 ◽  
Vol 21 (1) ◽  
pp. 232-234 ◽  
Author(s):  
G. Ruiz-Irastorza ◽  
C. Garea ◽  
J. J. Alonso ◽  
J. L. Hernandez ◽  
K. Aguirrebengoa ◽  
...  
Keyword(s):  
Septic Shock ◽  
Pasteurella Multocida ◽  
Healthy Woman

Pasteurella multocida septic shock after a cat scratch in an elderly otherwise healthy woman: a case report

2008 ◽  
Vol 26 (3) ◽  
pp. 380.e1-380.e3 ◽  
Author(s):  
Jenaro A. Fernández-Valencia ◽  
Sebastian García ◽  
Salvio Prat
Keyword(s):  
Septic Shock ◽  
Case Report ◽  
Pasteurella Multocida ◽  
Healthy Woman

1748: AN UNUSUAL CAUSE OF SEPTIC SHOCK IN AN OTHERWISE HEALTHY WOMAN

2016 ◽  
Vol 44 (12) ◽  
pp. 512-512
Author(s):  
Abdul Hasan Siddiqui ◽  
Amina Saqib ◽  
Tahir Khan ◽  
Ambreen khalil
Keyword(s):  
Septic Shock ◽  
Healthy Woman

scholarly journals Capnocytophaga canimorsusas Cause of Fatal Sepsis

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
Moritz Hundertmark ◽  
Tatjana Williams ◽  
Anja Vogel ◽  
Maria Moritz ◽  
Peter Bramlage ◽  
...  
Keyword(s):  
Septic Shock ◽  
Multiorgan Failure ◽  
Healthy Woman ◽  
Young Individual ◽  
Capnocytophaga Canimorsus ◽  
Dog Bites ◽  
First Case ◽  
Fatal Sepsis

A rare consequence of dog bites is the infection withCapnocytophaga canimorsus, and only a few cases have been documented. We describe a 41-year-old, formerly healthy woman who died from septic shock and multiorgan failure. It is the first case of a young individual without obvious immunosuppression.

Low-Dose Steroids Cut Mortality in Septic Shock

2006 ◽  
Vol 36 (19) ◽  
pp. 24
Author(s):  
BRUCE JANCIN
Keyword(s):  
Septic Shock ◽  
Low Dose

Septic shock patient and ultrasound in the emergency room

2016 ◽  
Vol 37 (S 01) ◽  
Author(s):  
M Algaba Montes ◽  
AÁ Oviedo García ◽  
M Patricio Bordomás
Keyword(s):  
Septic Shock ◽  
Emergency Room ◽  
Septic Shock Patient

Combination of Antibiotic Treatment with the Thrombin Inhibitor Recombinant Hirudin for the Therapy of Experimental Klebsiella pneumoniae Sepsis

1994 ◽  
Vol 71 (06) ◽  
pp. 768-772 ◽  
Author(s):  
Gerhard Dickneite ◽  
Jörg Czech
Keyword(s):  
Septic Shock ◽  
Klebsiella Pneumoniae ◽  
Organ Failure ◽  
Therapeutic Effect ◽  
Disseminated Intravascular Coagulation ◽  
Post Infection ◽  
Thrombin Inhibitor ◽  
Bolus Administration ◽  
Bacterial Burden ◽  
Recombinant Hirudin

SummaryRats which were infected with the gramnegative pathogen Klebsiella pneumoniae develop disseminated intravascular coagulation (DIC), multi-organ failure (MOF) and finally die in a septic shock. We investigated the therapeutic effect of antibiotic (tobramycin) treatment combined with the infusion of the highly specific thrombin inhibitor rec. hirudin. Although administration of 2 mg/kg tobramycin alone leads to a decrease of the bacterial burden, DIC could not be prevented. Infusion of rec. hirudin (0.25 mg/kg x h) for 4 h (start of treatment 1 h post infection), in addition to a bolus administration of tobramycin, led to an amelioration of DIC parameters as fibrinogen, thrombin-antithrombin complex (TAT) and platelets. Serum transaminase levels (GOT, GPT) as a marker of MOF were significantly improved by rec. hirudin, the T50 value increased from 17 h in the tobramycin group to 42 h in the tobramycin + rec. hirudin giuup, muilality rates were 90% or 60%, respectively. Combination of heparin (10011/kg x h) and tobramycin was not effective on survival.

Functional Characterization of a Variant Factor XII (F XII Locarno) in a Cross Reacting Material Positive F XII Deficient Plasma

1992 ◽  
Vol 67 (02) ◽  
pp. 219-225 ◽  
Author(s):  
Walter A Wuillemin ◽  
Miha Furlan ◽  
Hans Stricker ◽  
Bernhard Lämmle
Keyword(s):  
Dextran Sulfate ◽  
Functional Characterization ◽  
Healthy Woman ◽  
Chain Molecule ◽  
Plasma Kallikrein ◽  
Factor Xii ◽  
Single Chain ◽  
Sulfate Adsorption ◽  
Prolonged Incubation ◽  
Functional Studies

SummaryThe plasma of a healthy woman was found to contain half normal factor XII (FXII) antigen level (0.46 U/ml) without any FXII clotting activity (<0.01 U/ml). The variant FXII in this plasma, denoted as FXII Locarno, was partially characterized by immunological and functional studies on the proposita’s plasma. FXII Locarno is a single chain molecule with the same size (M r = 80 kDa) as normal FXII. Isoelectric focusing suggested an excess of negative charge in the variant FXII as compared to normal FXII. In contrast to FXII in normal plasma, FXII Locarno was not proteolytically cleaved upon prolonged incubation of proposita’s plasma with dextran sulfate. Adsorption to kaolin was similar for both, abnormal and normal FXII. Incubation of the proposita’s plasma with dextran sulfate and exogenous plasma kallikrein showed normal cleavage of FXII Locarno outside of the tentative disulfide loop Cys340-Cys467, but only partial cleavage within this disulfide loop. Furthermore, plasma kallikrein-cleaved abnormal FXII showed neither amidolytic activity nor proteolytic activity against factor XI and plasma prekallikrein.These results suggest a structural alteration of FXII Locarno, affecting the plasma kallikrein cleavage site Arg353-Val354 and thus formation of activated FXII (a-FXIIa).

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