O1 SINGLE CELL CHARACTERISATION OF ABDOMIAL AORTIC ANEURYSMS BY MASS CYTOMETRY (CYTOF) REVEALS A CHRONIC INFLAMMATORY CELL INFILTRATE PREDOMINATED BY T AND B CELLS

2018 ◽  
Vol 114 (suppl_2) ◽  
pp. S1-S1
Author(s):  
Ismail Cassimjee ◽  
Regent Lee ◽  
David Ahern ◽  
Patricia Green ◽  
Inhye Park ◽  
...  
1999 ◽  
Vol 91 (2) ◽  
pp. 330-334 ◽  
Author(s):  
Demetrios C. Nikas ◽  
Umberto De Girolami ◽  
Amir A. Zamani ◽  
Geraldine S. Pinkus ◽  
Lorenzo Bello ◽  
...  

✓ This 63-year-old man presented with complaints of “having a feeling of falling backward” over a 3-month period. Results of his general physical examination, laboratory studies, and neurological examination were unremarkable. A magnetic resonance image revealed a 1.8 × 1.4 × 1.2—cm enhancing mass in the posterior third ventricle just above the corpora quadrigemina. The pineal gland was found to be diffusely enlarged at operation and separable from the posterior thalamus and was totally resected. The patient had an uneventful postoperative course but continues to be somewhat confused. The lesion consisted of a remarkable chronic inflammatory cell infiltrate permeating the pineal lobules and was composed of T and B lymphocytes, macrophages, eosinophils, and mast cells. Immunoperoxidase studies did not demonstrate Langerhans cells, and a search for microorganisms was unrevealing. There was no evidence of neoplasia; results of immunostaining for germ cell markers and other tumor-associated antigens were negative.


JMS SKIMS ◽  
2019 ◽  
Vol 22 (1) ◽  
Author(s):  
Besina Yasin Syed ◽  
Naheena Bashir

Xanthogranulomatous inflammation is a special form of chronic inflammation that is destroying normal tissue of affected organs which are replaced by chronic inflammatory cell infiltrate admixed with foci or sheets of foam cells, fibroplasia, chronic inflammatory cell infiltrate and vascular proliferation. Only a few cases of xanthogranulomatous oophoritis have been reported.We report a case of 35 year old female who presented with lower abdominal pain and polymennorhea.A total hysterectomy with bilateral salpingoopherectomy was performed on the suspicion of an ovarian neoplasm.


2018 ◽  
Vol 20 (1) ◽  
Author(s):  
Silvia Bosello ◽  
Cristiana Angelucci ◽  
Gina Lama ◽  
Stefano Alivernini ◽  
Gabriella Proietti ◽  
...  

2021 ◽  
Vol 7 (7) ◽  
pp. 533
Author(s):  
Ailish Williams ◽  
Helen Rogers ◽  
David Williams ◽  
Xiao-Qing Wei ◽  
Damian Farnell ◽  
...  

Previous research into the inflammatory cell infiltrate of chronic hyperplastic candidosis (CHC) determined that the immune response is primarily composed of T cells, the majority of which are T helper (CD4+) cells. This present investigation used immunohistochemistry to further delineate the inflammatory cell infiltrate in CHC. Cells profiled were those expressing IL-17A cytokine, EBI3 and IL-12A subunits of the IL-35 cytokine, and FoxP3+ cells. Squamous cell papilloma (with Candida infection) and oral lichen planus tissues served as comparative controls to understand the local immune responses to Candida infection. The results demonstrated that Candida-induced inflammation and immune regulation co-exist in the oral mucosa of CHC and that high prevalence of cells expressing the EBI3 cytokine subunit may play an important role in this regulation. This balance between inflammation and immune tolerance toward invading Candida in the oral mucosa may be critical in determining progress of infection.


PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e108069 ◽  
Author(s):  
Tom-Ole Løvås ◽  
Jo C. Bruusgaard ◽  
Inger Øynebråten ◽  
Kristian Gundersen ◽  
Bjarne Bogen

1987 ◽  
Vol 18 (5) ◽  
pp. 511-520 ◽  
Author(s):  
Debra A. Bell ◽  
Thomas J. Flotie ◽  
Atul K. Bhan

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