P172 ESOPHAGEAL SUBMUCOSAL LIPOMA AND CONCOMITANT INEFFECTIVE MOTILITY: LAPAROSCOPIC TRANSHIATAL ENUCLEATION

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
Bernardi Daniele ◽  
Porta Matteo ◽  
Asti Emanuele ◽  
Siboni Stefano ◽  
Lazzari Veronica ◽  
...  

Abstract Aim To describe an unusual case of benign esophageal submucosal tumor. Background Esophageal lipomas account for less than 1% of benign tumors of the esophagus, which represent less than 1% of all esophageal neoplasms. The presence of a concomitant esophageal motility disorder may be underestimated in patients with benign esophageal submucosal tumors. Case report A 77-year-old man was referred for a 12-year history of daily heartburn, occasional dysphagia progressively worsening during the last few months, and more recent onset of epigastric pain, regurgitation, and weight loss. Empirical therapy with proton-pump inhibitors was ineffective. The GERD-HRQL score was 22. Physical examination was unremarkable. Upper gastrointestinal endoscopy showed a soft submucosal mass in the posterior wall of the lower third of the esophagus, 3 cm above the esophago-gastric junction. The endoscopic finding was confirmed by a chest CT scan that documented a submucosal esophageal lesion with luminal narrowing. High resolution manometry did not reveal EGJ obstruction but showed a pan-esophageal pressurization in 100% of the swallows. The patient underwent laparoscopic transhiatal enucleation of a 11x4 cm mass, suture repair of the esophageal muscle layer, posterior cruroplasty, and 270° Toupet fundoplication. The postoperative course was uneventful. A gastrographin swallow study on day 1 showed the normal esophagogastric transit and the absence of leaks. The patient was discharged on postoperative day 2. Pathology confirmed the clinical suspicion of esophageal lipoma. At 3-month follow-up visit the GERD-HRQL score was 7 and the patient was very pleased with the results of the operation. Conclusion Esophageal lipoma is very rare. Laparoscopic transhiatal enucleation was feasible and safe in our experience. The choice of a Toupet fundoplication was justified by the finding of ineffective esophageal motility on high-resolution manometry.

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
Carlo Galdino Riva ◽  
Stefano Siboni ◽  
Veronica Lazzari ◽  
Marco Sozzi ◽  
Emanuele Asti ◽  
...  

Abstract Aim The aim of this study was to evaluate esophageal motility before and after Magnetic Sphincter Augmentation (MSA) for medically refractory Gastro-Esophageal Reflux Disease (GERD). Background and Methods MSA (LINX® Reflux Management System) is intended for patients with chronic GERD with incomplete symptom relief from proton-pump inhibitors (PPI) and abnormal acid exposure. A prospectively collected database of patients who underwent MSA between 2007 and 2019 was queried. All patients who completed pre- and post-operative high-resolution manometry (HRM) were included in the study. Additional investigations included Health-Related Quality of Life (GERD-HRQL) questionnaire, Functional Outcome Swallowing Scale (FOSS), upper gastrointestinal endoscopy, barium swallow, and 24-96 hours pH-study. Data were analyzed using Wilcoxon signed rank test and McNemar test. Results Forty-five patients met the inclusion criteria. The median follow-up was 10 months (IQR 6). Compared to baseline, there was a statistically significant reduction in PPI use (p=0.000), rate of heartburn (p=0.000), regurgitation (p=0.008), and extra-esophageal symptoms (p=0.000). Only three (6.7%) patients required dietary changes. The GERD-HRQL score significantly improved (p=0.000). There was a significant increase in the Lower Esophageal Sphincter (LES) competency, including LES length (p=0.004) and Esophago-gastric Contractile Integral ((EGJ-CI) (p=0.000). A significant increase in integrated relaxation pressure (IRP) (p=0.000), mean Distal Contractile Integral (DCI) (p=0.008) and intrabolus pressure (p=0.000) was also found. Thirteen (28.9%) patients presented pre-operative Ineffective Esophageal Motility (IEM) and five of them resolved postoperatively. Two patients (4.4%) developed IEM after surgery: both had IRP and DCI values within normal limits, and one of them complained of dysphagia. However, the GERD-HRQL score recovered in both patients. Conclusion MSA was clinically effective in relieving both typical and atypical GERD symptoms. LES competency increased after MSA. EGJ outflow obstruction was uncommon and not associated with symptoms. Finally, ineffective esophageal motility may reverse to normal after MSA.


2014 ◽  
Vol 20 (1) ◽  
pp. 79-86 ◽  
Author(s):  
Alessandra Elvevi ◽  
Ivana Bravi ◽  
Aurelio Mauro ◽  
Delia Pugliese ◽  
Andrea Tenca ◽  
...  

2015 ◽  
Vol 30 (7) ◽  
pp. 2703-2710 ◽  
Author(s):  
Masato Hoshino ◽  
Nobuo Omura ◽  
Fumiaki Yano ◽  
Kazuto Tsuboi ◽  
Se Ryung Yamamoto ◽  
...  

2020 ◽  
Vol 158 (6) ◽  
pp. S-1095-S-1096
Author(s):  
Wei-Yi Lei ◽  
Jen-Hung Wang ◽  
Ming-Wun Wong ◽  
Chih-Hsun Yi ◽  
Tso-Tsai Liu ◽  
...  

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