scholarly journals Role of the radiopharmacist in myocardial perfusion imaging safety as part of a multidisciplinary team

2021 ◽  
Vol 22 (Supplement_3) ◽  
Author(s):  
A Jimenez-Heffernan ◽  
C Salgado-Garcia ◽  
T Aroui-Luquin ◽  
E Sanchez De Mora ◽  
AM Santos-Bueno

Abstract Funding Acknowledgements Type of funding sources: None. Background Vasodilator stress agents have limitations and clinical contraindications that must be identified before patients undergo myocardial perfusion imaging (MPI). Clinical pharmacy may be viewed as part of radiopharmacy practice enabling radiopharmacists to recognize patients with an increased risk of complications and identify relative and absolute contraindications for vasodilator cardiac stress. Purpose Assessment of the role of the radiopharmacist in a multidisciplinary team focused on the safe performance of regadenoson and adenosine stress MPI. Methods We studied 800 patients undergoing SPECT MPI (55.9% female, mean age 67.1 ±11.4 y, range: 24-90 y). Gender, age, medical history, medications, drug allergies and contraindications for stress testing were registered and the resulting recommendations were reported to the nuclear physician in charge of the patient. Results The table displays the findings and recommendations to the nuclear physician. No contraindications were found in 77.2% of patients. Conclusion With a systematic approach, the radiopharmacist detected a drug interaction or clinical contraindication in approximately 25% of patients and the reported recommendations were well received and accepted by the nuclear physicians who changed their approach with the resulting increased patient safety. The clinical activity of radiopharmacists can be enhanced and many opportunities will be identified. Physicians and nurses should be aware of the potential role of radiopharmacists as clinical providers in Nuclear Medicine departments.

2021 ◽  
Vol 18 (5) ◽  
pp. 31-37
Author(s):  
Raluca Mititelu ◽  
Cătălin Mazilu ◽  
Adina Mazilu ◽  
Silviu Stanciu

Abstract Diabetes mellitus is a complex pathology with increasing incidence, associated with an increased risk of coronary heart disease. Myocardial perfusion imaging (MPI) is an important diagnostic tool for the evaluation of coronary artery disease (CAD), with a high prognostic value. Objective. The aim of this study was to evaluate the role of stress-rest MPI in the assessment of patients with DM and suspected or confirmed CAD. Method. We performed a retrospective analysis of 128 patients who underwent stress-rest MPI in our department, all of them with coronary angiography (CA) available. All patients underwent stress rest myocardial perfusion SPECT using a 1-day or 2-day protocol. The radiopharmaceuticals used were 99m-Tc-MIBI or tetrofosmin. The study was performed with a gated protocol SPECT, synchronous with the ECG, using a dual-head gamma camera. Patients were divided in 4 subgroups based on the presence of DM and of significant CA changes. Results. In the group of patients with significant coronary disease on CA and previously diagnosed DM, number of perfusion defects on the stress-rest MPI were higher and also the presence of systolic disfunction and the severity of defects. Our results support the idea that the severity and extent of myocardial perfusion defects are greater in diabetic patients than in non-diabetic patients. Conclusions. We can consider myocardial perfusion SPECT with 99mTc-labeled agents as a feasible method for the diagnosis and evaluation of CAD and for the management of diabetic patients.


2006 ◽  
Vol 3 (2) ◽  
pp. 68-72
Author(s):  
Jennifer Mieres ◽  
Leslee J Shaw ◽  
Robert C Hendel ◽  
D Douglas Miller ◽  
Robert Bonow ◽  
...  


Author(s):  
Caroline E. Veltman ◽  
Berlinda J. de Wit-van der Veen ◽  
Albert de Roos ◽  
Joanne D. Schuijf ◽  
Ernst E. van der Wall

2006 ◽  
Vol 3 (1) ◽  
pp. 66-70
Author(s):  
Jennifer Mieres ◽  
Leslee J Shaw ◽  
Robert C Hendel ◽  
D Douglas Miller ◽  
Robert Bonow ◽  
...  


2018 ◽  
Vol 63 (18) ◽  
pp. 185011 ◽  
Author(s):  
Brendan L Eck ◽  
Raymond F Muzic ◽  
Jacob Levi ◽  
Hao Wu ◽  
Rachid Fahmi ◽  
...  

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