scholarly journals P1535 Interventricular interaction can result in right ventricular dysfunction in interventricular septum involved myocardial infarction patient

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
C S Park ◽  
A Gwon ◽  
H S Ahn ◽  
G H Kim ◽  
J S Cho ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Right Ventricular ◽  
Longitudinal Strain ◽  
Ventricular Dysfunction ◽  
Global Longitudinal Strain ◽  
Interventricular Septum ◽  
Right Ventricular Dysfunction ◽  
Free Wall ◽  
Right Ventricular Free Wall

Abstract Background Previous studies revealed that interventricular septal thickness is related to right ventricular dysfunction after anterior myocardial infarction. This finding suggest that interventricular septal function can affect right ventricular function in myocardial infarction patients. We assumed that right ventricular free wall strain values measured using dedicated software can be affected in the setting of ischemic insult on interventricular septum in long-term follow up. Methods The patients diagnosed as acute myocardial infarction due to left anterior descending artery disease who underwent successful revascularization were enrolled. Echocardiographic exams were performed at least 2 times, within 72 hours and 1 year after the revascularization. Strain values of interventricular septum and right ventricular free wall were derived from the raw-dicom images. The analysis was performed using the dedicated software for the measurement of right ventricular strain. Results Total 65 patients were enrolled. The values of global left ventricular strain were increased after the follow up. There were no changes in global longitudinal strain of the right ventricle. But longitudinal stain values acquired from right ventricular free walls were decreased even the strain values measured at left ventricle and interventricular septum were improved. Conclusion Interventricular septal dysfunction due to ischemic injury can affect long term right ventricular dysfunction. This finding suggests the interventricular dependence between cardiac chambers and can provide the development of heart failure in myocardial infarction patient even after the successful revascularization. Strain values of both ventricles Left ventricle after revascularization (n = 65) 1 year later (n = 65) P values Global longitudinal strain (%) -12.84 ± 4.50 -15.62 ± 4.45 <0.001 Septal longitudinal strain (%) -10.77 ± 5.96 -14.02 ± 5.26 <0.001 Right ventricle Global longitudinal strain (%) -19.36 ± 4.57 -19.47 ± 4.83 0.872 Septal longitudinal strain (%) -14.82 ± 4.48 -16.43 ± 6.03 0.055 Free wall longitudinal strain (%) -20.23 ± 5.33 -17.82 ± 5.70 0.010 Abstract P1535 Figure. Right ventricular segmental strain

scholarly journals Right ventricular contractility decreases during exercise in patients with non-advanced idiopathic pulmonary fibrosis

2020 ◽  
Author(s):  
Sandra Barros Cobra ◽  
Marcelo Palmeira Rodrigues ◽  
Felipe Xavier Melo ◽  
Nathali Mireise Costa Ferreira ◽  
Cesar Augusto Melo Silva
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Right Ventricular ◽  
Speckle Tracking ◽  
Longitudinal Strain ◽  
Ventricular Dysfunction ◽  
Global Longitudinal Strain ◽  
Right Ventricular Dysfunction ◽  
Peak Exercise ◽  
Ventricular Contractility

Introduction: Early right ventricular dysfunction in non-advanced patients with idiopathic pulmonary fibrosis has not been fully elucidated. Thus, we aimed to assess right ventricular functions in idiopathic pulmonary fibrosis patients and controls by speckle-tracking strain echocardiography at rest and peak exercise. Methods: We conducted a cross-sectional study in 20 idiopathic pulmonary fibrosis patients without oxygen use, blood oxygen saturation levels ≥92% at rest, and modified Medical Research Council score ≤3 and enrolled 10 matched controls. Transthoracic echocardiography images were acquired at rest and during a cardiopulmonary exercise test. We analyzed two-dimensional echocardiographic parameters and right ventricular function using the global longitudinal strain assessed by the two-dimensional speckle-tracking technique. Results: In the control group, we found normal values of global longitudinal strain (GLS) at rest and at peak exercise, the latter being much more negative (-23.6&plusmn2.2% and -26.8&plusmn3.1%, respectively; p<0.001). By contrast, GLS values in the idiopathic pulmonary fibrosis group increased from -21.1&plusmn3.8% at rest to -17.0&plusmn4.5% at peak exercise (p<0.001). The exercise revealed a difference between the two groups as the mean GLS values moved during peak exercise in opposite directions. Patients with idiopathic pulmonary fibrosis got worse, whereas control patients presented improved right ventricular contractility. Conclusions: Right ventricular dysfunction was unveiled by speckle-tracking echocardiography during exercise in non-advanced idiopathic pulmonary fibrosis patients. We suggest that this reflects an inadequate right ventricular-arterial coupling decreasing the right ventricular longitudinal contraction during exercise in these patients. This parameter may be useful as an early index of suspected pulmonary hypertension.  

scholarly journals Right ventricular dysfunction and long-term risk of death

2020 ◽  
Vol 10 (5) ◽  
pp. 1646-1658
Author(s):  
Jason L. Sanders ◽  
Martin Koestenberger ◽  
Stephan Rosenkranz ◽  
Bradley A. Maron
Keyword(s):  
Right Ventricular ◽  
Ventricular Dysfunction ◽  
Right Ventricular Dysfunction ◽  
Risk Of Death
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