scholarly journals Characterization of the ligand-binding site of the transferrin receptor in Trypanosoma brucei demonstrates a structural relationship with the N-terminal domain of the variant surface glycoprotein

1997 ◽  
Vol 16 (24) ◽  
pp. 7272-7278 ◽  
Author(s):  
D. Salmon
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Trypanosoma Brucei ◽  
Transferrin Receptor ◽  
Structural Relationship ◽  
Surface Glycoprotein ◽  
Variant Surface Glycoprotein ◽  
Ligand Binding Site ◽  
Terminal Domain

Synthesis and structural characterization of triple-helical peptides which mimic the ligand binding site of the human macrophage scavenger receptor

Tetrahedron ◽  
1997 ◽  
Vol 53 (42) ◽  
pp. 14263-14274 ◽  
Author(s):  
Hironobu Hojo ◽  
Yoshiko Akamatsu ◽  
Kiyoshi Yamauchi ◽  
Masayoshi Kinoshita ◽  
Shunji Miki ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Structural Characterization ◽  
Scavenger Receptor ◽  
Human Macrophage ◽  
Ligand Binding Site ◽  
Helical Peptides ◽  
Macrophage Scavenger Receptor

scholarly journals Characterization of the Ligand Binding Site of the Bovine IgA Fc Receptor (bFcαR)

2004 ◽  
Vol 279 (52) ◽  
pp. 54018-54022 ◽  
Author(s):  
H. Craig Morton ◽  
Richard J. Pleass ◽  
Jenny M. Woof ◽  
Per Brandtzaeg
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Fc Receptor ◽  
Ligand Binding Site

scholarly journals Chemical characterization of ligand binding site fragments from turkey β-adrenergic receptor

FEBS Letters ◽  
1989 ◽  
Vol 246 (1-2) ◽  
pp. 166-170 ◽  
Author(s):  
Y. Eshdat ◽  
M.-P. Chapot ◽  
A.D. Strosberg
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Adrenergic Receptor ◽  
Chemical Characterization ◽  
Ligand Binding Site

Lumazine proteins from photobacteria: localization of the single ligand binding site to the N-terminal domain

2007 ◽  
Vol 388 (12) ◽  
Author(s):  
Boris Illarionov ◽  
Wolfgang Eisenreich ◽  
Martina Wirth ◽  
Chan Yong Lee ◽  
Young Eun Woo ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Ligand Binding Site ◽  
Terminal Domain

scholarly journals Cloning and characterization of a variant surface glycoprotein expression site from Trypanosoma equiperdum.

1986 ◽  
Vol 6 (8) ◽  
pp. 2950-2956 ◽  
Author(s):  
A Raibaud ◽  
G Buck ◽  
T Baltz ◽  
H Eisen
Keyword(s):  
Trypanosoma Brucei ◽  
Southern Blot Analysis ◽  
Surface Glycoprotein ◽  
Variant Surface Glycoprotein ◽  
African Trypanosomes ◽  
Active Expression ◽  
Expression Site ◽  
Trypanosoma Equiperdum ◽  
Dna Fragment

Variant surface glycoprotein (VSG) genes of African trypanosomes are expressed when they are inserted into one of several telomere-linked expression sites. We cloned and characterized an 11-kilobase (kb) DNA fragment located upstream of an expressed VSG gene. A DNA sequence of 1.8 kb that is located immediately upstream of the inserted VSG gene contains sequences homologous to the 76-base-pair repeats described as being upstream of VSG genes in Trypanosoma brucei (D. A. Campbell, M. P. Van Bree, and J. C. Boothroyd, Nucleic Acids Res. 12:2759-2774). There are no such sequences elsewhere in the 11-kb cloned region. Southern blot analysis using probes from the cloned region revealed multiple unlinked copies of the same or very similar regions. At least three of these are located near telomeres, and two have been shown to be used for the expression of known Trypanosoma equiperdum VSG genes. Like VSG genes, the upstream sequences themselves can be duplicated and deleted. The choice of expression site to be used by a duplicated VSG gene is nonrandom; the site used for expression of the parental VSG gene is strongly favored for use in the daughter variant. Furthermore, even when the parental expression site is not used, the VSG gene occupying it is replaced. Thus, an active expression site is a preferential target for gene conversion in the next variation event.

scholarly journals Identification of a Ligand-Binding Site on theStaphylococcus aureusDnaG Primase C-Terminal Domain

Biochemistry ◽  
2017 ◽  
Vol 56 (7) ◽  
pp. 932-943
Author(s):  
Jonathan Catazaro ◽  
Jessica Periago ◽  
Matthew D. Shortridge ◽  
Bradley Worley ◽  
Andrew Kirchner ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Binding Site ◽  
Ligand Binding Site ◽  
Terminal Domain

2·9 Å resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei

1990 ◽  
Vol 216 (1) ◽  
pp. 141-160 ◽  
Author(s):  
Douglas Freymann ◽  
James Down ◽  
Mark Carrington ◽  
Isabel Roditi ◽  
Mervyn Turner ◽  
...  
Keyword(s):  
Trypanosoma Brucei ◽  
Surface Glycoprotein ◽  
Variant Surface Glycoprotein ◽  
Terminal Domain ◽  
Resolution Structure
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