scholarly journals Bleeding patterns after vaginal misoprostol for treatment of early pregnancy failure

2004 ◽  
Vol 19 (7) ◽  
pp. 1655-1658 ◽  
Author(s):  
A.R. Davis
Keyword(s):  
Early Pregnancy ◽  
Pregnancy Failure ◽  
Early Pregnancy Failure ◽  
Vaginal Misoprostol

COMPARISON OF MIFEPRISTONE (200mg) FOLLOWED BY MISOPROSTOL (800µg) 6 HRS LATER WITH 24 HRS LATER IN EARLY PREGNANCY FAILURE

2021 ◽  
pp. 80-82
Author(s):  
Hari Charan Ray ◽  
Himadri Nayek ◽  
Amit Kumar Mandal ◽  
Sankar Nath Mitra
Keyword(s):  
Early Pregnancy ◽  
Gestational Age ◽  
Medical Abortion ◽  
P Value ◽  
Missed Abortion ◽  
Pregnancy Failure ◽  
Early Pregnancy Failure ◽  
Single Centre Study ◽  
Vaginal Misoprostol ◽  
Blighted Ovum

INTRODUCTION: Early pregnancy failure (EPF) is an inclusive term that comprises incomplete, complete, or inevitable spontaneous abortion; anembryonic gestation (blighted ovum); and embryonic demise (missed abortion) at less than 14 weeks 1. It is one of the most common complications of pregnancy, accounting for approximately 15% to 20% of clinically recognized pregnancies 1,2. Many EPFs occur before pregnancies have been clinically recognized (that is, women mistake them for “late cycles”). AIMS & OBJECTIVES: To compare the efcacy between mifepristone 200mg orally followed by misoprostol 800µg vaginally 6 hrs later with mifepristone 200mg orally followed by misoprostol 800µg vaginally 24 hrs later in early pregnancy failure for termination up to 9 weeks of gestation. To reduce unusual blood loss. To reduce surgical intervention in case of early pregnancy failure. MATERIALS & METHODS: Hospital based Prospective randomiSe comparative single centre study. Department of Obstetrics and Gynecology Midnapore Medical College and Hospital. One year from January 2019 to February 2020 for data collection and six month for data analysis. Mother attended the Gynae OPD clinic and Obstetrics emergency with features of early pregnancy failure. The sample size was 50, with 25 patients in each group. RESULTS:We found that the table 4 shows the distribution according to gestational age. The main indication for which medical abortion was done in our study is early pregnancy failure (Blighted ovum) and missed abortion. Majority of patients were in the gestational age between 8-9 weeks with 48 % of women who underwent 6 hour interval regimen and 40% of women who underwent 24 hour interval regimen. P value documented is 0.849 which is not signicant. There was no signicant difference between two groups regarding gestational age (p value=0.849). SUMMARY AND CONCLUSION: Vaginal Misoprostol can be safely administered 6 hours following Mifepristone instead of waiting for 24 hours. Efcacy in achieving complete abortion rate is almost equal to 24 hours regimen and most acceptable from patient's side also. Additionally, women are less likely to experience side effects the earlier the misoprostol is used. Women can now have more exibility when using mifepristone and vaginal misoprostol for medical abortion

scholarly journals Comparison of efficacy of 600 and 800 micrograms vaginal misoprostol in early pregnancy failure in SMGS: a tertiary health care hospital in Jammu, India

2022 ◽  
Author(s):  
Reema Khajuria ◽  
Arushi Suri ◽  
Rohini Jaggi
Keyword(s):  
Side Effects ◽  
Early Pregnancy ◽  
Care Hospital ◽  
Fetal Demise ◽  
Pregnancy Failure ◽  
Early Pregnancy Failure ◽  
Group A ◽  
Vaginal Misoprostol ◽  
Group B ◽  
Labour Room

Background: Misoprostol use in early pregnancy failure is varied and dose is not well established. Aim of this study was to compare efficacy and side effects of 600 versus 800 micrograms vaginal misoprostol in early pregnancy failure.Methods: A randomized prospective observational study was conducted in the postgraduate department of obstetrics and gynaecology, SMGS hospital Jammu from November 2018 to October 2019 after getting approval from the ethical committee. Hundred patients (50 in group A and 50 in group B) admitted in labour room before 12 weeks of gestation with an ultrasound diagnosis of early fetal demise (missed abortion or brightened ovum) were treated medically with different doses of vaginal misoprostol.Results: The success rate in patients in group A is 72% and group B is 88%, p=0.045 (difference is statistically significant). Patients who required suction and evacuation were 28% in group A and 12% in group B.Conclusions: Use of misoprostol for medical management of 1st trimester missed/anembryonic is an effective, cheap, safe and convenient alternative to surgical evacuation. It was concluded that 800 micrograms vaginal misoprostol is more effective than 600 micrograms vaginal misoprostol. But 800 micrograms misoprostol has more side effects than 600 micrograms vaginal misoprostol.

scholarly journals Comparison of different regimes of misoprostol for the termination of early pregnancy failure

2014 ◽  
Vol 70 (4) ◽  
pp. 360-363 ◽  
Author(s):  
Nandaram Seervi ◽  
Nupur Hooja ◽  
Lata Rajoria ◽  
Asha Verma ◽  
Kusum Malviya ◽  
...  
Keyword(s):  
Early Pregnancy ◽  
Pregnancy Failure ◽  
Early Pregnancy Failure

Misoprostol treatment for early pregnancy failure does not impair future fertility

2014 ◽  
Vol 30 (4) ◽  
pp. 316-319 ◽  
Author(s):  
Ilia Bord ◽  
Michael Gdalevich ◽  
Ravit Nahum ◽  
Simion Meltcer ◽  
Eyal Y. Anteby ◽  
...  
Keyword(s):  
Early Pregnancy ◽  
Pregnancy Failure ◽  
Future Fertility ◽  
Early Pregnancy Failure

Genetic abnormalities seen on CVS in early pregnancy failure

2018 ◽  
Vol 33 (13) ◽  
pp. 2142-2147
Author(s):  
Alexis C. Gimovsky ◽  
Amelie Pham ◽  
Sindy C. Moreno ◽  
Sara Nicholas ◽  
Amanda Roman ◽  
...  
Keyword(s):  
Early Pregnancy ◽  
Pregnancy Failure ◽  
Genetic Abnormalities ◽  
Early Pregnancy Failure

scholarly journals THE STUDY OF EFFICACY OF SUBLINGUAL MISOPROSTOL IN TERMINATION OF EARLY PREGNANCY

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Arti Kumari ◽  
Usha Kumari ◽  
Anupama Sinha
Keyword(s):  
Side Effects ◽  
Spontaneous Abortion ◽  
Early Pregnancy ◽  
Gestational Age ◽  
High Efficacy ◽  
Missed Abortion ◽  
Pregnancy Failure ◽  
Products Of Conception ◽  
Early Pregnancy Failure ◽  
Sublingual Misoprostol

Introduction: Nearly 20% of all confirmed pregnancies end in spontaneous abortion. Misoprostol’s use in early pregnancy failure is varied and dose and route are not well established. AIM: To study the efficacy of sublingual misoprostol in causing expulsion of products of conception in early pregnancy failure. Methods: Women with an ultrasound diagnosis of early pregnancy failure, less than 12 weeks gestation were included in the study. Tablet Misoprostol 600 mcg was given six hourly sublingually for 3 doses. All observations were noted and analyzed. Results: Mean gestational age was 7.946+1.2 weeks. Mean induction abortion interval was 18.241+1.2 hours. Women with gestational age six to eight weeks had least mean induction-abortion interval time of 17.38+2.86. Mean dose required was 1560mcg. Efficacy of protocol was 92.85% in achieving complete abortion. Conclusion: The regime had 92.85% efficacy, acceptability (90%) and few side effects. Thus by using a lower dose and appropriate interval between two doses (six hours), the side effects were lessened with high efficacy. Keywords: Efficacy, Missed Abortion, Misoprostol.

Sign in / Sign up

Export Citation Format

Share Document