scholarly journals F-150LONG-TERM SURVIVAL FOLLOWING OPEN VERSUS VIDEO-ASSISTED THORACOSCOPIC LOBECTOMY AFTER INDUCTION THERAPY FOR NON-SMALL CELL LUNG CANCER

2015 ◽  
Vol 21 (suppl_1) ◽  
pp. S42-S42
Author(s):  
Chi-Fu Jeffrey Yang ◽  
R.R. Meyerhoff ◽  
T. Singhapricha ◽  
C.B. Toomey ◽  
A. Kumar ◽  
...  
2015 ◽  
Vol 49 (6) ◽  
pp. 1615-1623 ◽  
Author(s):  
Chi-Fu Jeffrey Yang ◽  
Robert Ryan Meyerhoff ◽  
Nicholas Ryan Mayne ◽  
Terry Singhapricha ◽  
Christopher B. Toomey ◽  
...  

2006 ◽  
Vol 82 (1) ◽  
pp. 214-219 ◽  
Author(s):  
Rebecca P. Petersen ◽  
DuyKhanh Pham ◽  
Eric M. Toloza ◽  
William R. Burfeind ◽  
David H. Harpole ◽  
...  

2021 ◽  
pp. 021849232199738
Author(s):  
Tran Minh Bao Luan ◽  
Ho Tat Bang ◽  
Nguyen Lam Vuong ◽  
Le Tien Dung ◽  
Nguyen Trung Tin ◽  
...  

Background Video-assisted thoracoscopic surgery lobectomy combined with lymphadenectomy is widely utilized worldwide for treating non-small cell lung cancer. We evaluated the long-term survival outcomes of this approach and determined the prognostic factors of overall survival. Methods This prospective observational study was performed in patients with non-small cell lung cancer who were subjected to video-assisted lobectomy and lymphadenectomy from 2012 to 2016. Independent prognostic factors were determined via uni- and multivariable Cox models. Results There were 109 patients with the mean age of 59.2 years and males accounted for 54.1%. Postoperative staging determined 22.9% of stage IA, 31.2% of stage IB, 16.5% of stage IIA and 29.4% of stage IIIA. Median follow-up time was 27 months. The overall survival rate after 1, 2, 3, 4 and 5 years was 100%, 85.9%, 65.3%, 55.9% and 55.9%, respectively. In univariable analysis, smoking (hazard ratio (HR) [95% confidence interval (CI)]: 2.50 [1.18–5.31]), Tumor--nodes--metastases (TNM) stage (IIA: 7.60 [1.57–36.9]; IIIA: 14.3 [3.28–62.7] compared to IA), histological differentiation (moderately differentiated: 4.91 [1.04–23.2]; poorly differentiated: 8.25 [1.91–35.6] compared to well differentiated), lymph node size ≥1 cm (8.22 [3.11–21.7]), tumour size ≥3 cm (4.24 [1.01–17.9]), radical lymphadenectomy (6.67 [3.14–14.2]) were identified as prognostic factors of the long-term survival. In multivariable analysis, only radical lymphadenectomy was an independent prognostic factor (HR [95% CI]: 3.94 [1.41–11.0]). Conclusion Video-assisted thoracoscopic lobectomy combined with lymphadenectomy is feasible, safe and effective for the treatment of non-small cell lung cancer. The long-term outcomes of this method are favourable, especially at the early stage of cancer.


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