MHC class II hierarchy of superantigen presentation predicts efficiency of infection with mouse mammary tumor virus

1994 ◽  
Vol 6 (9) ◽  
pp. 1403-1407 ◽  
Author(s):  
Werner Held ◽  
Gary A. Waandere ◽  
H. Robson MacDonald ◽  
Hans Acha-Orbea
Keyword(s):  
Mhc Class Ii ◽  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Class Ii ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus

scholarly journals Association of Mouse Mammary Tumor Virus Superantigen with MHC Class II During Biosynthesis

2001 ◽  
Vol 166 (5) ◽  
pp. 3309-3314 ◽  
Author(s):  
Ping-Ning Hsu ◽  
Paula Wolf Bryant ◽  
Natalie Sutkowski ◽  
Brian McLellan ◽  
Hidde L. Ploegh ◽  
...  
Keyword(s):  
Mhc Class Ii ◽  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Class Ii ◽  
Mammary Tumor Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus

scholarly journals Regions of Mouse Mammary Tumor Virus Superantigen Involved in Interaction with the Major Histocompatibility Complex Class II I-A Molecule

2002 ◽  
Vol 76 (21) ◽  
pp. 11172-11175 ◽  
Author(s):  
Susanne Wirth ◽  
Annelyse Vessaz ◽  
Claude Krummenacher ◽  
Frédéric Baribaud ◽  
Hans Acha-Orbea ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility Complex Class ◽  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Class Ii ◽  
Complex Class ◽  
Mammary Tumor Virus ◽  
Histocompatibility Complex ◽  
Mouse Mammary Tumor ◽  
Tumor Virus

ABSTRACT To study the major histocompatibility complex class II I-E dependence of mouse mammary tumor virus (MMTV) superantigens, we constructed hybrids between the I-E-dependent MMTV(GR) and the I-E-independent mtv-7 superantigens and tested them in vivo. Our results suggest that, although the C-terminal third mediates I-A interaction, additional binding sites are located elsewhere in the superantigen.

Electron Microscopy of the Nucleic Acid of Mouse Mammary Tumor Virus

1968 ◽  
Vol 26 ◽  
pp. 22-23
Author(s):  
N. H. Sarkar ◽  
Dan H. Moore
Keyword(s):  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Ammonium Acetate ◽  
Dry Weight ◽  
Mouse Tumor ◽  
Mammary Tumor Virus ◽  
Rna Molecules ◽  
Mouse Mammary Tumor ◽  
Tumor Virus ◽  
The Subject

Mouse mammary tumor virus (MTV) is believed to contain about 0.8% single stranded ribonucleic acid (RNA). This value of RNA content was estimated on a dry weight basis. The subject of this report is an attempt to visualize the RNA molecules of MTV particles.MTV particles were isolated from RIII mouse (tumor incidence approximately 80%) milk according to the method described by Lyons and Moore. Purified virions from 5 ml of milk were finally suspended in 0.2 ml of PBS, pH 7.4 and was mixed with an equal volume of pronase (5 mg/ml). This mixture was incubated at 37°C for an hour. RNA was extracted three times using freshly prepared cold phenol. It was then treated three times with cold ethyl ether to remove any trace of phenol. The RNA thus extracted was divided into two parts. One part was diluted four fold with 8M urea to avoid aggregation of the molecules. The other part was left untreated. Both samples were then mixed with an equal volume of 1M ammonium acetate, adjusted to pH 8.0 with NH3 containing chymotrypsin at a concentration of 0.01%.

A novel V beta 2-specific endogenous mouse mammary tumor virus which is capable of producing a milk-borne exogenous virus.

1995 ◽  
Vol 69 (11) ◽  
pp. 7269-7273 ◽  
Author(s):  
N Niimi ◽  
W Wajjwalku ◽  
Y Ando ◽  
N Nakamura ◽  
M Ueda ◽  
...  
Keyword(s):  
Mammary Tumor ◽  
Mouse Mammary Tumor Virus ◽  
Mammary Tumor Virus ◽  
Exogenous Virus ◽  
Mouse Mammary Tumor ◽  
Tumor Virus ◽  
Beta 2
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