Synergistic interaction of antibiotics with nasal penetration to methicillin-sensitive and methicillin-resistant Staphylococcus aureus

1991 ◽  
Vol 27 (4) ◽  
pp. 558-560 ◽  
Author(s):  
JOSEPH W. CHOW ◽  
MEGAN HILF ◽  
VICTOR L. YU
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Synergistic Interaction ◽  
Methicillin Resistant

In vitro and in vivo synergistic interaction of substituted chalcone derivatives with norfloxacin against methicillin resistant Staphylococcus aureus

RSC Advances ◽  
2015 ◽  
Vol 5 (8) ◽  
pp. 5830-5845 ◽  
Author(s):  
Rashmi Gaur ◽  
Vivek Kumar Gupta ◽  
Anirban Pal ◽  
Mahendra Padurang Darokar ◽  
Rajendra Singh Bhakuni ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Efflux Pump ◽  
Synergistic Interaction ◽  
Bacterial Cells ◽  
Methicillin Resistant ◽  
Chalcone Derivatives

The present investigation shows that certain substituted chalcone derivatives diminish the escalation of bacterial cellsviainhibiting bacterial efflux pump and exhibit a synergistic interaction with norfloxacin.

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