scholarly journals Nalidixic acid-susceptible, ciprofloxacin-resistant Neisseria gonorrhoeae strain in the UK

2005 ◽  
Vol 56 (2) ◽  
pp. 437-437 ◽  
Author(s):  
P. L. Ragunathan ◽  
C. Ison ◽  
D. M. Livermore
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Nalidixic Acid ◽  
Gonorrhoeae Strain ◽  
The Uk

scholarly journals Clinical Neisseria gonorrhoeae isolate with a N. meningitidis porA gene and no prolyliminopeptidase activity, Sweden, 2011 – danger of false-negative genetic and culture diagnostic results

2012 ◽  
Vol 17 (9) ◽  
Author(s):  
D Golparian ◽  
E Johansson ◽  
M Unemo
Keyword(s):  
Neisseria Gonorrhoeae ◽  
False Negative ◽  
Gonorrhoeae Strain ◽  
Negative Results ◽  
False Negative Results ◽  
Gonorrhoeae Isolate

We describe a Neisseria gonorrhoeae strain, found in Sweden in 2011, that harbours a N. meningitidis porA gene causing false-negative results in PCRs targeting the gonococcal porA pseudogene. Furthermore, the strain had no prolyliminopeptidase (PIP) activity that many commercial biochemical kits for species verification in culture rely on. Enhanced awareness of the spread of such strains and screening for them can be crucial.

scholarly journals Non-cultural detection and molecular genotyping of Neisseria gonorrhoeae from a piece of clothing

2007 ◽  
Vol 56 (4) ◽  
pp. 487-490 ◽  
Author(s):  
Iona M. C. Martin ◽  
Ellie Foreman ◽  
Vicky Hall ◽  
Anne Nesbitt ◽  
Greta Forster ◽  
...  
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Molecular Detection ◽  
Definitive Diagnosis ◽  
Sequence Type ◽  
Detection Methods ◽  
Legal Cases ◽  
Immunological Tests ◽  
The Uk ◽  
Relationship Of ◽  
The Relationship

Isolation of Neisseria gonorrhoeae is currently the gold standard for the definitive diagnosis of gonorrhoea and for use in medico-legal cases in the UK. Molecular detection methods are used increasingly but are untested as evidence of infection in a court of law. An isolate of N. gonorrhoeae was obtained from a child and an article of clothing from an adult male who was suspected of sexual abuse of the child. Biochemical and immunological tests were used to confirm the isolate as N. gonorrhoeae. Amplification by PCR using two targets, cppB and ompIII, was used both as further confirmation of the isolate and to detect the presence of gonococcal-specific DNA from the clothing. The relationship of the gonococcal DNA from the child and the adult was investigated using genotyping (N. gonorrhoeae multi-antigen sequence typing; NG-MAST), including a nested PCR for the por gene. Both samples were indistinguishable by NG-MAST and shared the same sequence type, 403. This is the first report of molecular detection and genotyping of N. gonorrhoeae on an article of clothing, which resulted in conviction of the man for sexual assault.

scholarly journals A Neisseria gonorrhoeae strain with a meningococcal mtrR sequence

2014 ◽  
Vol 63 (8) ◽  
pp. 1113-1115 ◽  
Author(s):  
Ella Trembizki ◽  
Christine Doyle ◽  
Amy Jennison ◽  
Helen Smith ◽  
John Bates ◽  
...  
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Gonorrhoeae Strain

scholarly journals First Neisseria gonorrhoeae strain with resistance to cefixime causing gonorrhoea treatment failure in Austria, 2011

2011 ◽  
Vol 16 (43) ◽  
Author(s):  
M Unemo ◽  
D Golparian ◽  
A Stary ◽  
A Eigentler
Keyword(s):  
Public Health ◽  
United Kingdom ◽  
Antimicrobial Resistance ◽  
Neisseria Gonorrhoeae ◽  
Treatment Failure ◽  
Effective Treatment ◽  
Therapeutic Failure ◽  
Health Control ◽  
Gonorrhoeae Strain ◽  
The United Kingdom

We describe the first cefixime-resistant Neisseria gonorrhoeae strain in Austria that caused treatment failure. It follows the first five cases in Europe of cefixime treatment failure, reported in Norway in 2010 and the United Kingdom in 2011. Effective treatment of gonorrhoea is crucial for public health control and, at present, requires substantially enhanced awareness, more frequent test-of-cure, interaction with experts after therapeutic failure, tracing and therapy of contacts, and surveillance of gonococcal antimicrobial resistance and treatment failures worldwide.

scholarly journals Identification of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain FC428, China

2019 ◽  
Vol 25 (7) ◽  
pp. 1427-1429 ◽  
Author(s):  
Shao-Chun Chen ◽  
Yan Han ◽  
Liu-Feng Yuan ◽  
Xiao-Yu Zhu ◽  
Yue-Ping Yin
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Gonorrhoeae Strain
Sign in / Sign up

Export Citation Format

Share Document