Successful Treatment of Fungal Peritonitis in CAPD Using Oral Fluconazole

1990 ◽  
Vol 5 (7) ◽  
pp. 555-555 ◽  
Author(s):  
M. C. Venning ◽  
M. Ford ◽  
F. K. Gould
Keyword(s):  
Successful Treatment ◽  
Fungal Peritonitis ◽  
Oral Fluconazole

Candida parapsilosis: A rare cause of arthritis and its successful treatment with oral fluconazole

2021 ◽  
Vol 35 (1) ◽  
pp. 42
Author(s):  
KhuraijamRanjana Devi ◽  
NingthoujamPriyolakshmi Devi ◽  
KJoy Singh Akoijam ◽  
PukhrambamPratita Devi ◽  
LongjamNilachandra Singh
Keyword(s):  
Successful Treatment ◽  
Candida Parapsilosis ◽  
Oral Fluconazole

Fungal Peritonitis in Peritoneal Dialysis Patients: Successful Prophylaxis with Fluconazole, as Demonstrated by Prospective Randomized Control Trial

2010 ◽  
Vol 30 (6) ◽  
pp. 619-625 ◽  
Author(s):  
César Restrepo ◽  
Jose Chacon ◽  
Gilberto Manjarres
Keyword(s):  
Peritoneal Dialysis ◽  
Chronic Kidney Disease Stage ◽  
Disease Stage ◽  
Oral Antibiotic ◽  
Peritoneal Fibrosis ◽  
Exit Site Infection ◽  
Fungal Peritonitis ◽  
Oral Fluconazole ◽  
Bacterial Peritonitis ◽  
Significant Difference

ObjectivesTo determine whether oral administration of the antifungal fluconazole during the entire period of treatment of bacterial peritonitis (BP), exit-site infection (ESI), or tunnel infection (TI) prevents later appearance of fungal peritonitis (called secondary) in patients with chronic kidney disease stage 5 in a peritoneal dialysis (PD) program.Patients and MethodsAll patients treated in the PD program in RTS Ltda Sucursal Caldas, during the period 1 June 2004 to 30 October 2007 were screened. Patients that had infectious bacterial complications (BP, ESI, TI) were included in a prospective randomized trial to receive or not receive oral fluconazole (200 mg every 48 hours) throughout the time period required by the administration of therapeutic antibiotics via any route. It was evaluated whether the fungal peritonitis complication appeared within 30 – 150 days following the end of antibacterial treatment. Based on local results, the sample size necessary to obtain statistically significant results was determined to be 434 episodes of peritonitis.ResultsThe 434 episodes of peritonitis presented between the previously specified dates and during this same period there were 174 ESI or TI, of which only 52 received oral antibiotic treatment. Information in relation to consumption of antibiotics for purposes other than BP, ESI, and TI was not reliable and thus this variable was excluded. Among the episodes of peritonitis, 402 (92.6%) were of bacterial origin and 32 (7.3%) were mycotic, mainly Candida species [30 (93.75%)]. Of the fungal peritonitis, 14 (43.73%) were primary (without prior use of antibiotics) and 18 (56.25%) were secondary. In the group of patients that received prophylaxis with fluconazole (210 for BP and 26 for ESI or TI), only 3 occurrences of fungal peritonitis were observed within 30 – 150 days of its administration, which is opposite to the group without prophylaxis (210 for BP and 26 for ESI or TI), in which 15 occurrences of fungal peritonitis were detected. Statistical analysis of the group of patients with BP found comparisons of the proportions of those receiving fluconazole (0.92%) or not (6.45%) presented a highly significant difference in favor of prophylaxis ( p = 0.0051, Z = 2.8021). Given that only 1 patient in each group with ESI or TI, with or without prophylaxis, presented the complication fungal peritonitis, it was concluded that this result was not statistically significant. During laparoscopic surgery attempting reintroduction of the peritoneal catheter, it was found that 11 patients had severe adhesions or peritoneal fibrosis leading to obliteration of the peritoneal cavity. In 19 patients, reintroduction of the catheter was possible and the patients returned to PD without consequence.ConclusionIn patients with bacterial peritonitis, administration of prophylactic oral fluconazole throughout the time they received antibiotics significantly prevented the appearance of secondary fungal peritonitis.

Successful treatment of sporotrichosis with oral fluconazole: a report of three cases

1993 ◽  
Vol 128 (3) ◽  
pp. 352-356 ◽  
Author(s):  
L.G.M. CASTRO ◽  
W. BELDA ◽  
L.C. CUCE ◽  
S.A.P. SAMPAIO ◽  
D.A. STEVENS
Keyword(s):  
Successful Treatment ◽  
Oral Fluconazole

Successful Treatment of Fungal Peritonitis in CAPD by Intravenous, Intraperitoneal, and Intracatheter Administration of Amphotericin B. A Case Report

1995 ◽  
Vol 15 (2) ◽  
pp. 187-187 ◽  
Author(s):  
J.T. Caramoril ◽  
M. Barros e Silva ◽  
M.J.D.B. Felipe ◽  
T. Sadatsune ◽  
A.C. Montelli ◽  
...  
Keyword(s):  
Case Report ◽  
Amphotericin B ◽  
Successful Treatment ◽  
Fungal Peritonitis

Successful treatment of disseminated cryptococcosis with high-dose oral fluconazole

AIDS ◽  
1993 ◽  
Vol 7 (12) ◽  
pp. 1685-1687 ◽  
Author(s):  
O Sitbon ◽  
T Fourme ◽  
P Bourée ◽  
L Du Pasquier ◽  
S Salmeron
Keyword(s):  
Successful Treatment ◽  
High Dose ◽  
Oral Fluconazole ◽  
Dose Oral
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