scholarly journals Effect of single-dose rituximab on steroid-dependent minimal-change nephrotic syndrome in adults

2012 ◽  
Vol 28 (5) ◽  
pp. 1225-1232 ◽  
Author(s):  
T. Takei ◽  
M. Itabashi ◽  
T. Moriyama ◽  
C. Kojima ◽  
S. Shiohira ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Single Dose ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Steroid Dependent

scholarly journals Single dose of rituximab in children with steroid-dependent minimal change nephrotic syndrome

2016 ◽  
Vol 5 (2) ◽  
pp. 237-242 ◽  
Author(s):  
Xiao-Ling Niu ◽  
Sheng Hao ◽  
Ping Wang ◽  
Wei Zhang ◽  
Gui-Mei Guo ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Single Dose ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Steroid Dependent

scholarly journals Efficacy of Semiannual Single Fixed Low-Dose Rituximab Therapy in Steroid-Dependent Minimal Change Nephrotic Syndrome: A Case Series

2018 ◽  
Vol 8 (3) ◽  
pp. 230-237 ◽  
Author(s):  
Ryosuke Usui ◽  
Yohei Tsuchiya ◽  
Kosaku Nitta ◽  
Minako Koike
Keyword(s):  
Nephrotic Syndrome ◽  
Low Dose ◽  
Chemotherapy Regimen ◽  
Case Series ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Cell Hyperplasia ◽  
Conventional Dose ◽  
Steroid Dependent ◽  
Refractory Nephrotic Syndrome

The frequency of using rituximab to treat refractory nephrotic syndrome has recently been increasing, and the conventional dose of rituximab used to treat it, 375 mg/m2 body surface area once weekly for 4 weeks, has been modelled on the chemotherapy regimen for B-cell non-Hodgkin’s lymphoma. The dose and intervals of rituximab in refractory nephrotic syndrome remain controversial. Clear lymphoma cell hyperplasia is seen in lymphoma patients, but not in nephrotic syndrome patients. Since we thought that it might be possible to reduce the dose of rituximab if only used for the purpose of depleting CD20-positive B cells in nephrotic patients’ peripheral blood, we tried semiannually with a single fixed rituximab dose of 100 mg/body, and a complete remission was attained in 3 cases without treatment with prednisolone or cyclosporine. Our report strongly suggests considering appropriate dose and interval of rituximab therapy in the treatment of steroid-dependent nephrotic syndrome.

Single infusion of rituximab for persistent steroid-dependent minimal-change nephrotic syndrome after long-term cyclosporine

2010 ◽  
Vol 25 (3) ◽  
pp. 539-544 ◽  
Author(s):  
Shuichiro Fujinaga ◽  
Daishi Hirano ◽  
Naoto Nishizaki ◽  
Koichi Kamei ◽  
Shuichi Ito ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Single Infusion ◽  
Steroid Dependent

scholarly journals Tacrolimus as a steroid-sparing agent for adults with steroid-dependent minimal change nephrotic syndrome

2008 ◽  
Vol 23 (6) ◽  
pp. 1919-1925 ◽  
Author(s):  
X. Li ◽  
H. Li ◽  
J. Chen ◽  
Q. He ◽  
R. Lv ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Steroid Dependent ◽  
Steroid Sparing

Mesangial myofibroblastic transformation in steroid-dependent minimal change nephrotic syndrome

2000 ◽  
Vol 33 (2) ◽  
pp. 102-107 ◽  
Author(s):  
K. Naruse ◽  
Mikiya Fujieda ◽  
Eriko Miyazaki ◽  
Yoshihiro Hayashi ◽  
Makoto Toi ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Minimal Change Nephrotic Syndrome ◽  
Minimal Change ◽  
Steroid Dependent
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