scholarly journals MP84920 YEARS OF GROWTH HORMONE TREATMENT IN CHILDREN WITH CHRONIC KIDNEY DISEASE IN POLAND - RESULTS OF NATIONAL MULTICENTRE STUDY

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii746-iii746
Author(s):  
Beata Leszczynska ◽  
Dominika Adamczuk ◽  
Piotr Skrzypczyk ◽  
Anna Majcher ◽  
Beata Pyrżak ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Kidney Disease ◽  
Multicentre Study ◽  
Growth Hormone Treatment ◽  
Hormone Treatment

Efficacy of Growth Hormone Treatment in Children With Chronic Kidney Disease: Tunisian Experience

2021 ◽  
Vol 58 (12) ◽  
pp. 1140-1142
Author(s):  
Abir Boussetta ◽  
R. Laamouri ◽  
M. Jellouli ◽  
O. Naija ◽  
T. Gargah
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Kidney Disease ◽  
Growth Hormone Treatment ◽  
Hormone Treatment

scholarly journals Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease

2019 ◽  
Vol 15 (9) ◽  
pp. 577-589 ◽  
Author(s):  
Jens Drube ◽  
◽  
Mandy Wan ◽  
Marjolein Bonthuis ◽  
Elke Wühl ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Clinical Practice ◽  
Kidney Disease ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Practice Recommendations

Short-term growth hormone treatment and microcirculation: Effects in patients with chronic kidney disease

2009 ◽  
Vol 78 (2) ◽  
pp. 246-252 ◽  
Author(s):  
Richard Nissel ◽  
Dagmar-Christiane Fischer ◽  
Andreas Puhlmann ◽  
Birgit Holdt-Lehmann ◽  
Andrea Mitzner ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Kidney Disease ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Short Term

P182125 YEARS OF GROWTH HORMONE TREATMENT IN CHILDREN WITH CHRONIC KIDNEY DISEASE IN POLAND - RESULTS OF NATIONAL MULTICENTER STUDY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Beata Leszczyńska ◽  
Maria Daniel ◽  
Anna Majcher ◽  
Beata Pyrzak ◽  
Maria Szczepanska ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Kidney Disease ◽  
Growth Velocity ◽  
Growth Hormone Treatment ◽  
Recombinant Human Growth Hormone ◽  
Human Growth ◽  
Hormone Treatment ◽  
Rhgh Therapy ◽  
Rhgh Treatment

Abstract Background and Aims Growth retardation is one of considerable problems in children with chronic kidney disease (CKD) with a great impact on life activity and quality of life. Recombinant human growth hormone (rhGH) treatment has been used for more than 30 years to improve growth velocity and final growth in children with CKD. In Poland rhGH therapy in children with CKD is available since 1994. The aim of the study was to assess growth velocity in all children with CKD treated with rhGH in Poland since 1994. Method We retrospectively analyzed 321 polish children with CKD (mean age: 10.2±7.60, 210 ♂ (65%) qualified to the rhGH therapy between 1994 and 2019. Among 321 children, 180 (56.1%) were on conservative treatment (CT), 118 (36.7%) on chronic dialysis (RRT) and 23 (7.2%) after kidney transplantation (KTx). In 240 (75%) patients who were treated continuously for at least 12 months we have evaluated: growth velocity and mean annual values of selected biochemical parameters. Results Mean height SDS at the beginning of the treatment was -2.73±1.04 SD, among children on CT -2.22±1.20, on RRT -2.9±1.11, after KTx -3.07±1.30. Mean time of rhGH treatment was 23±10.7 months. During one-year rhGH treatment mean growth velocity in 240 children was: 8.5 ± 2.7 cm (ΔSDS 0.78±1.02) and mean height SDS increased significantly (-2,73±1.04 vs. -1.92±1.11, p<0.0001). Children on CT did not differ significantly in age vs. children on RRT (10.66±3.40 vs. 10.26±3.61 years, p =0.972), and growth velocity was slower in RRT group expressed in cm (7.52±2.59 vs. 9.2±2.30, p<0.0001) and in ΔSDS (0.4±0.83 vs. 0.72±1.15, p=0.045). Growth velocity (ΔSDS) correlated negatively with age of rhGH initiation in children on CT (r=-0.40, p=0.008) and on RRT (r=-0.28, p=0.03). We found no significant relation between growth velocity and sex, cause of CKD, hemoglobin, total protein, albumin, urea, creatinine, calcium, phosphorus, Ca x P, PTH and alkaline phosphatase. Conclusion 1. Growth hormone treatment is highly effective in children with CKD especially those who are treated consevatively. 2. Early initiation of rhGH therapy is the crucial factor determining response to the treatment in children with CKD.

Growth hormone treatment in short children with chronic kidney disease

2008 ◽  
Vol 97 (9) ◽  
pp. 1159-1164 ◽  
Author(s):  
O Mehls ◽  
E Wühl ◽  
B Tönshoff ◽  
F Schaefer ◽  
R Nissel ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Kidney Disease ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Short Children

Growth Hormone Treatment in Short Children with Chronic Kidney Disease

2007 ◽  
pp. 407-421 ◽  
Author(s):  
Otto Mehls ◽  
Anders Lindberg ◽  
Richard Nissel ◽  
Elke Wühl ◽  
Franz Schaefer ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Growth Hormone ◽  
Kidney Disease ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Short Children
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