Stimulation of Glycosphingolipid Biosynthesis by L-Threo-1-Phenyl-2-Decanoylamino-1-Propanol and Its Homologs in B16 Melanoma Cells

1995 ◽  
Vol 117 (4) ◽  
pp. 766-773 ◽  
Author(s):  
Jin-ichi Inokuchi ◽  
Seigou Usuki ◽  
Masayuki Jimbo
Keyword(s):  
Melanoma Cells ◽  
B16 Melanoma ◽  
B16 Melanoma Cells ◽  
Glycosphingolipid Biosynthesis ◽  
Stimulation Of

Stimulation of pheomelanogenesis in cultured B16 melanoma cells by 4-tertiary butylcatechol

1985 ◽  
Vol 34 (19) ◽  
pp. 3517-3521 ◽  
Author(s):  
Takeshi Kawashima ◽  
Magnus M. Halldin ◽  
Kimie Fukuyama ◽  
Neal Castagnoli ◽  
Gerald A. Gellin ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
B16 Melanoma ◽  
B16 Melanoma Cells ◽  
Stimulation Of

scholarly journals Stimulation of melanogenesis by glycyrrhizin in B16 melanoma cells

2001 ◽  
Vol 33 (3) ◽  
pp. 131-135 ◽  
Author(s):  
Gi-Dong Jung ◽  
Jeong-Yeh Yang ◽  
Eun-Sup Song ◽  
Jin-Woo Park
Keyword(s):  
Melanoma Cells ◽  
B16 Melanoma ◽  
B16 Melanoma Cells ◽  
Stimulation Of

scholarly journals Stimulation of melanogenesis by scoparone in B16 melanoma cells

2006 ◽  
Vol 27 (11) ◽  
pp. 1467-1473 ◽  
Author(s):  
Jeong-yeh YANG ◽  
Jeung-hyun KOO ◽  
Young-gil SONG ◽  
Kang-beom KWON ◽  
Ju-hyung LEE ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
B16 Melanoma ◽  
B16 Melanoma Cells ◽  
Stimulation Of

Stimulation of Melanogenesis by the Citrus Flavonoid Naringenin in Mouse B16 Melanoma Cells

2006 ◽  
Vol 70 (6) ◽  
pp. 1499-1501 ◽  
Author(s):  
Kenji OHGUCHI ◽  
Yukihiro AKAO ◽  
Yoshinori NOZAWA
Keyword(s):  
Melanoma Cells ◽  
B16 Melanoma ◽  
B16 Melanoma Cells ◽  
Stimulation Of

scholarly journals Elucidation of Melanogenesis-Associated Signaling Pathways Regulated by Argan Press Cake in B16 Melanoma Cells

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2697
Author(s):  
Thouria Bourhim ◽  
Myra O. Villareal ◽  
Chemseddoha Gadhi ◽  
Hiroko Isoda
Keyword(s):  
Signaling Pathways ◽  
Press Cake ◽  
Global Gene Expression ◽  
Melanoma Cells ◽  
B16 Melanoma ◽  
Dependent Manner ◽  
Melanin Biosynthesis ◽  
B16 Melanoma Cells ◽  
Pigmentary Disorders ◽  
Argan Oil

The beneficial effect on health of argan oil is recognized worldwide. We have previously reported that the cake that remains after argan oil extraction (argan press-cake or APC) inhibits melanogenesis in B16 melanoma cells in a time-dependent manner without cytotoxicity. In this study, the global gene expression profile of B16 melanoma cells treated with APC extract was determined in order to gain an understanding of the possible mechanisms of action of APC. The results suggest that APC extract inhibits melanin biosynthesis by down-regulating microphthalmia-associated transcription factor (Mitf) and its downstream signaling pathway through JNK signaling activation, and the inhibition of Wnt/β-catenin and cAMP/PKA signaling pathways. APC extract also prevented the transport of melanosomes by down-regulating Rab27a expression. These results suggest that APC may be an important natural skin whitening product and pharmacological agent used for clinical treatment of pigmentary disorders.

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