Successful treatment of systemic sclerosis digital ulcers and pulmonary arterial hypertension with endothelin receptor antagonist bosentan

Arterial Hypertension ◽

Receptor Antagonist ◽

Successful Treatment ◽

Digital Ulcers ◽

Endothelin Receptor ◽

SAT0463 Initial Therapy with an Endothelin Receptor Antagonist (ERA) is Associated with Worse Outcomes in Patients with Systemic Sclerosis and Pulmonary Arterial Hypertension: Observations from the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Cohort (Pharos)

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2015-eular.2538 ◽

2015 ◽

Vol 74 (Suppl 2) ◽

pp. 828.1-828

Author(s):

M.R. Lammi ◽

L.A. Saketkoo ◽

S.C. Mathai ◽

R.T. Domsic ◽

V. Steen ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Systemic Sclerosis ◽

Arterial Hypertension ◽

Receptor Antagonist ◽

Initial Therapy ◽

Endothelin Receptor ◽

Effects of the endothelin receptor antagonist bosentan on hemodynamics and exercise capacity in Japanese patients with mildly symptomatic pulmonary arterial hypertension

Heart and Vessels ◽

10.1007/s00380-014-0544-1 ◽

2014 ◽

Vol 30 (6) ◽

pp. 798-804 ◽

Cited By ~ 6

Author(s):

Masaru Hatano ◽

Hidehiro Yamada ◽

Keiichi Fukuda ◽

Koichiro Yoshioka ◽

Masanori Funauchi ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Exercise Capacity ◽

Japanese Patients ◽

Endothelin Receptor ◽

SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension

European Heart Journal ◽

10.1093/eurheartj/ehx025 ◽

2017 ◽

Vol 38 (15) ◽

pp. 1147-1155 ◽

Cited By ~ 27

Author(s):

Nazzareno Galiè ◽

Pavel Jansa ◽

Tomás Pulido ◽

Richard N. Channick ◽

Marion Delcroix ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Disease Progression ◽

Endothelin Receptor ◽

Haemodynamic Parameters ◽

Pharmacokinetic and pharmacodynamic evaluation of macitentan, a novel endothelin receptor antagonist for the treatment of pulmonary arterial hypertension

Expert Opinion on Drug Metabolism & Toxicology ◽

10.1517/17425255.2015.1000859 ◽

2015 ◽

Vol 11 (3) ◽

pp. 437-449 ◽

Cited By ~ 15

Author(s):

Patricia N Sidharta ◽

Stephan Krähenbühl ◽

Jasper Dingemanse

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Endothelin Receptor ◽

Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension

Respiratory Research ◽

10.1186/1465-9921-10-129 ◽

2009 ◽

Vol 10 (1) ◽

Cited By ~ 5

Author(s):

Annette S Droste ◽

David Rohde ◽

Mirko Voelkers ◽

Arthur Filusch ◽

Thomas Bruckner ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Endothelin Receptor ◽

Novel Dual Endothelin Receptor Antagonist Macitentan Reverses Severe Pulmonary Arterial Hypertension in Rats

Journal of Cardiovascular Pharmacology ◽

10.1097/fjc.0000000000000141 ◽

2014 ◽

Vol 64 (5) ◽

pp. 473-480 ◽

Cited By ~ 8

Author(s):

Mutsumi Kunita-Takanezawa ◽

Kohtaro Abe ◽

Yoshitaka Hirooka ◽

Yukimitsu Kuwabara ◽

Katsuya Hirano ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Severe Pulmonary Arterial Hypertension

Endothelin Receptor ◽

Pulmonary Arterial ◽

Corrigendum to ‘‘An overview of the preclinical toxicity and potential carcinogenicity of sitaxentan (Thelin®), a potent endothelin receptor antagonist developed for pulmonary arterial hypertension” [Regul. Toxicol. Pharmacol. 2012, 95–103]

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2012.07.012 ◽

2012 ◽

Vol 64 (3) ◽

pp. 490

Author(s):

Keith Owen ◽

David M. Cross ◽

Mazin Derzi ◽

Elizabeth Horsley ◽

Fiona L. Stavros

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Endothelin Receptor ◽

The new endothelin receptor antagonist macitentan: Prospects for therapy of pulmonary arterial hypertension

Terapevticheskii arkhiv ◽

10.17116/terarkh201688789-97 ◽

2016 ◽

Vol 88 (7) ◽

pp. 89

Author(s):

S. N. Avdeev

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Endothelin Receptor ◽

Oral Treprostinil for the Treatment of Pulmonary Arterial Hypertension in Patients on Background Endothelin Receptor Antagonist and/or Phosphodiesterase Type 5 Inhibitor Therapy (The FREEDOM-C Study)

CHEST Journal ◽

10.1378/chest.11-2212 ◽

2012 ◽

Vol 142 (6) ◽

pp. 1383-1390 ◽

Cited By ~ 204

Author(s):

Victor F. Tapson ◽

Fernando Torres ◽

Fiona Kermeen ◽

Anne M. Keogh ◽

Roblee P. Allen ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Antagonist ◽

Inhibitor Therapy ◽

Endothelin Receptor ◽

Phosphodiesterase Type 5 Inhibitor ◽

Pulmonary Arterial ◽

Phosphodiesterase Type

Device Closure of a Large Atrial Septal Defect in a Patient with Severe Pulmonary Arterial Hypertension after 1 Year Use of an Oral Endothelin Receptor Antagonist

Journal of Cardiovascular Ultrasound ◽

10.4250/jcu.2013.21.3.140 ◽

2013 ◽

Vol 21 (3) ◽

pp. 140 ◽

Cited By ~ 6

Author(s):

In Hyun Jung ◽

Sang Yun Lee ◽

Sook Jin Lee ◽

Joo Young Lee ◽

Nam Jin Park ◽

...

Keyword(s):

Arterial Hypertension ◽

Atrial Septal Defect ◽

Receptor Antagonist ◽

Septal Defect ◽

Severe Pulmonary Arterial Hypertension

Endothelin Receptor ◽

Device Closure ◽

Pulmonary Arterial ◽