154. Perceptions of Testing to Predict Future Development of Rheumatoid Arthritis among the First-Degree Relatives of People with Rheumatoid Arthritis: A Qualitative Exploration

Rheumatology ◽  
2015 ◽  
Rheumatology ◽  
2014 ◽  
Vol 53 (9) ◽  
pp. 1646-1653 ◽  
Author(s):  
R. J. Stack ◽  
L. H. D. van Tuyl ◽  
M. Sloots ◽  
L. A. van de Stadt ◽  
W. Hoogland ◽  
...  

2019 ◽  
Vol 22 (11) ◽  
pp. 1990-2000 ◽  
Author(s):  
Jeimy A. Chaparro‐Sanabria ◽  
Wilson Bautista‐Molano ◽  
Juan M. Bello‐Gualtero ◽  
Lorena Chila‐Moreno ◽  
Diana M. Castillo ◽  
...  

Chemistry ◽  
2020 ◽  
Vol 2 (2) ◽  
pp. 203-218 ◽  
Author(s):  
Tina P. Andrejević ◽  
Biljana Đ. Glišić ◽  
Miloš I. Djuran

Gold complexes have been traditionally employed in medicine, and currently, some gold(I) complexes, such as auranofin, are clinically used in the treatment of rheumatoid arthritis. In the last decades, both gold(I) and gold(III) complexes with different types of ligands have gained considerable attention as potential antitumor agents, showing superior activity both in vitro and in vivo to some of the clinically used agents. The present review article summarizes the results achieved in the field of synthesis and evaluation of gold complexes with amino acids and peptides moieties for their cytotoxicity. The first section provides an overview of the gold(I) complexes with amino acids and peptides, which have shown antiproliferative activity, while the second part is focused on the activity of gold(III) complexes with these ligands. A systematic summary of the results achieved in the field of gold(I/III) complexes with amino acids and peptides could contribute to the future development of metal complexes with these biocompatible ligands as promising antitumor agents.


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