Use of the CT images for BNCT calculation: development of BNCT treatment planning system and its applications to dose calculation for voxel phantoms

Purpose: Point dose calculation in the Treatment Planning System (TPS) is performed using Computed Tomography (CT) images because CT images data have the tissue electron density information. The effect of CT imaging protocols on the calculation of point doses in TPS is one of the most important subjects that was evaluated in this study. Materials and Methods: CT scan imaging was performed from cylindrical water phantom using three scanner systems and different imaging technical parameters. The CT images data were irradiated in TPS to delivering a 200 cGy radiation dose to the center of the phantom with 6 and 15MV X-Ray photon energy with multiple radiation fields and Monitor Unit (MU) were separately calculated. In the TPS, a virtual water phantom with the same characteristic as CT image phantom was simulated and irradiated with similar conditions. The difference in MU values obtained from two irradiation methods in TPS was compared with Wilcoxon nonparametric test. Results: Variations of mA, kV, Pitch, slice thickness, and kernel as CT imaging parameters have not significantly affected radiotherapy point dose calculation (<2%). CT imaging protocols as a thin slice, 80 kV, and sharp kernel have the greatest difference between CT image-based calculation and designed phantom calculation in TPS where wedge field and 6 MV photon energy were used. Conclusion: The use of CT images obtained with multiple protocols can be used without having a significant effect on the dose calculations of the treatment planning system.

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EP-1338: An independent check of point dose calculation for commissioning a brachytherapy treatment planning system

Radiotherapy and Oncology ◽

10.1016/s0167-8140(15)33644-6 ◽

2013 ◽

Vol 106 ◽

pp. S503

Author(s):

D. Piriyasang ◽

S. Sakulsingharoj ◽

S. Srisuwan

Keyword(s):

Treatment Planning ◽

Dose Calculation ◽

Planning System ◽

Treatment Planning System

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Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system

Radiation Oncology ◽

10.1186/s13014-021-01968-2 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Naonori Hu ◽

Hiroki Tanaka ◽

Ryo Kakino ◽

Syuushi Yoshikawa ◽

Mamoru Miyao ◽

...

Keyword(s):

Monte Carlo ◽

Treatment Planning ◽

Neutron Capture ◽

Gamma Ray ◽

Dose Calculation ◽

Planning System ◽

Treatment Planning System ◽

Neutron Capture Therapy ◽

Boron Neutron Capture ◽

Monte Carlo Dose Calculation

AbstractBoron neutron capture therapy (BNCT) for the treatment of unresectable, locally advanced, and recurrent carcinoma of the head and neck cancer has been approved by the Japanese government for reimbursement under the national health insurance as of June 2020. A new treatment planning system for clinical BNCT has been developed by Sumitomo Heavy Industries, Ltd. (Sumitomo), NeuCure® Dose Engine. To safely implement this system for clinical use, the simulated neutron flux and gamma ray dose rate inside a water phantom was compared against experimental measurements. Furthermore, to validate and verify the new planning system, the dose distribution inside an anthropomorphic head phantom was compared against a BNCT treatment planning system SERA and an in-house developed Monte Carlo dose calculation program. The simulated results closely matched the experimental results, within 5% for the thermal neutron flux and 10% for the gamma ray dose rate. The dose distribution inside the head phantom closely matched with SERA and the in-house developed dose calculation program, within 3% for the tumour and a difference of 0.3 Gyw for the brain.

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