scholarly journals Serotonin 2A and Sigma 1 Receptor Antagonists Synergize to Block the Acute Toxicity of Methamphetamine

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Azizi Ray
Keyword(s):  
Acute Toxicity ◽  
Receptor Antagonists ◽  
Sigma 1 Receptor ◽  
Sigma 1 ◽  
Serotonin 2A

scholarly journals Sigma-1 receptor antagonists haloperidol and chlorpromazine modulate the effect of glutoxim on NA+ transport in frog skin

2019 ◽  
Vol 484 (5) ◽  
pp. 629-632
Author(s):  
Z. I. Krutetskaya ◽  
A. V. Melnitskaya ◽  
V. G. Antonov ◽  
A. D. Nozdrachev
Keyword(s):  
Voltage Clamp ◽  
Frog Skin ◽  
Na Transport ◽  
Receptor Antagonists ◽  
Sigma 1 Receptor ◽  
Voltage Clamp Technique ◽  
Frog Skin Epithelium ◽  
Sigma 1 ◽  
Immunomodulatory Drug ◽  
First Time

Using voltage-clamp technique, the involvement of sigma-1 receptors in immunomodulatory drug glutoxim regulation of Na+ transport in frog skin was investigated. We have shown for the first time that preincubation of the frog skin with sigma-1 receptor antagonists – haloperidol or chlorpromazine – attenuates the stimulatory effect of glutoxim on Na+ transport. The results suggest the possible involvement of the sigma-1 receptors in glutoxim effect on Na+transport in frog skin epithelium.

Preliminary in vitro assessment of pharmacokinetic drug-drug interactions of EST64401 and EST64514, two sigma-1 receptor antagonists

Xenobiotica ◽  
2020 ◽  
pp. 1-40
Author(s):  
Raquel F. Reinoso ◽  
Sandra Yeste ◽  
Eva Ayet ◽  
María José Pretel ◽  
Ariadna Balada ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Receptor Antagonists ◽  
Sigma 1 Receptor ◽  
Sigma 1 ◽  
In Vitro Assessment ◽  
Pharmacokinetic Drug

scholarly journals Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice

2018 ◽  
Vol 21 (10) ◽  
pp. 938-948
Author(s):  
Pilar Sánchez-Blázquez ◽  
Elsa Cortés-Montero ◽  
María Rodríguez-Muñoz ◽  
Javier Garzón
Keyword(s):  
Receptor Antagonists ◽  
Sigma 1 Receptor ◽  
Sigma 1

Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists

2019 ◽  
Vol 144 ◽  
pp. 244-255 ◽  
Author(s):  
Darren M. Riddy ◽  
Anna E. Cook ◽  
David M. Shackleford ◽  
Tracie L. Pierce ◽  
Elisabeth Mocaer ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Histamine H3 Receptor ◽  
Sigma 1 Receptor ◽  
Receptor Affinity ◽  
Receptor Kinetics ◽  
H3 Receptor ◽  
Sigma 1 ◽  
Drug Receptor ◽  
Histamine H3

Preclinical Acute Toxicity Studies and Dosimetry Estimates of the Novel Sigma-1 Receptor Radiotracer, [18F]SFE

2006 ◽  
Vol 8 (5) ◽  
pp. 284-291 ◽  
Author(s):  
Rikki N. Waterhouse ◽  
Jun Zhao ◽  
Michael G. Stabin ◽  
Hanna Ng ◽  
Janice Schindler-Horvat ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
The Novel ◽  
Sigma 1 Receptor ◽  
Toxicity Studies ◽  
Sigma 1
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