scholarly journals Decreased Total Antioxidant Capacity and Increased Oxidative Stress and Serum Ferritin Levels in Untreated Chronic Hepatitis C Patients

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Isaias Dichi ◽  
Danielle Venturini ◽  
Andrea Colado Simão ◽  
Décio Sabbatini Barbosa ◽  
Edson Lopes Lavado ◽  
...  

2009 ◽  
Vol 55 (4) ◽  
pp. 1120-1127 ◽  
Author(s):  
Danielle Venturini ◽  
Andréa Name Colado Simão ◽  
Décio Sabbatini Barbosa ◽  
Edson Lopes Lavado ◽  
Victor Emanuel Soares Narciso ◽  
...  




Antioxidants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 77
Author(s):  
Jing-Hua Wang ◽  
Sung-Bae Lee ◽  
Dong-Soo Lee ◽  
Chang-Gue Son

Oxidative stress plays a pivotal role in the progression of chronic hepatitis B; however, it is unclear whether the status of blood oxidative stress and antioxidant components differs depending on the degree of hepatic fibrosis. To explore the relationship between oxidative stress/antioxidant capacity and the extent of hepatic fibrosis, fifty-four subjects with liver fibrosis (5.5 ≤ liver stiffness measurement (LSM) score ≤ 16.0 kPa) by chronic hepatitis B virus (HBV) were analyzed. From the analysis of eight kinds of serum oxidative stress/antioxidant profiles and liver fibrosis degrees, the level of total antioxidant capacity (TAC) reflected a negative correlation with the severity of hepatic fibrosis (Pearson correlation, r = −0.35, p = 0.01). Moreover, TAC showed higher sensitivity (73.91%) than the aspartate transaminase (AST) to platelet ratio index (APRI, 56.52%) in the receiver operating characteristic (ROC) curves. Interestingly, the TAC level finely reflected the fibrosis degree in inactive carriers (HBV DNA < 2000 IU/mL), while the APRI did in active carriers (HBV DNA > 2000 IU/mL). In conclusion, TAC is a promising biomarker for evaluating the progression of liver fibrosis in patients with HBV, and this finding may indicate the involvement of TAC-composing factors in the pathogenesis of hepatic fibrosis in chronic HBV carriers.



2016 ◽  
Vol 53 ◽  
pp. 106-107
Author(s):  
B.A.M. El Awady ◽  
B. Hussein ◽  
E. El-Seidi ◽  
Y. Abou-Hamed


1999 ◽  
Vol 30 (5) ◽  
pp. 774-782 ◽  
Author(s):  
Giuseppe Barbaro ◽  
Gabriella Di Lorenzo ◽  
Michela Ribersani ◽  
Maurizio Soldini ◽  
Giuseppe Giancaspro ◽  
...  




Cureus ◽  
2021 ◽  
Author(s):  
Maria Gill ◽  
Javaria Sharafat ◽  
Faiza Ikram ◽  
Misbah Ul Qamar ◽  
Irum Rehman ◽  
...  


2006 ◽  
Vol 164 ◽  
pp. S76-S77
Author(s):  
Levent Gorenek ◽  
Ali Acar ◽  
Ahmet Aydin ◽  
Can Polat Eyigun ◽  
Aytac Cetinkaya ◽  
...  


2015 ◽  
Vol 46 (4) ◽  
pp. 259-268 ◽  
Author(s):  
Koji Uchino ◽  
Ryosuke Tateishi ◽  
Naoto Fujiwara ◽  
Tatsuya Minami ◽  
Masaya Sato ◽  
...  


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