scholarly journals Differential blood pressure response in normotensive rats and rats with angiotensin II‐dependent hypertension following systemic cannabinoid CB1 receptor blockade (1140.11)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Chris Schaich ◽  
Allyn Howlett ◽  
K. Brosnihan ◽  
Debra Diz
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Blood Pressure Response ◽  
Cb1 Receptor ◽  
Pressure Response ◽  
Receptor Blockade ◽  
Cannabinoid Cb1 Receptor

scholarly journals BLOOD PRESSURE RESPONSE TO [1-SARCOSINE, 8-ISOLEUCINE]ANGIOTENSIN II IN PATIENTS WITH LIVER CIRRHOSIS AND ASCITES

1979 ◽  
Vol 43 (1) ◽  
pp. 37-41 ◽  
Author(s):  
TAKESHI HATA ◽  
TOSHIO OGIHARA ◽  
HIROSHI MIKAMI ◽  
MITSUAKI NAKAMARU ◽  
TAKASHI MANDAI ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Liver Cirrhosis ◽  
Angiotensin Ii ◽  
Blood Pressure Response ◽  
Pressure Response

scholarly journals Blood pressure response to angiotensin II is enhanced in obese Zucker rats and is attributed to an aldosterone-dependent mechanism

2012 ◽  
Vol 166 (8) ◽  
pp. 2417-2429 ◽  
Author(s):  
Helge Müller-Fielitz ◽  
Margot Lau ◽  
Olaf Jöhren ◽  
Florian Stellmacher ◽  
Markus Schwaninger ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Zucker Rats ◽  
Obese Zucker Rats ◽  
Dependent Mechanism

Blood pressure responsiveness during the development of hypertension in the conscious spontaneously hypertensive rat

1985 ◽  
Vol 63 (10) ◽  
pp. 1258-1262 ◽  
Author(s):  
Corey B. Toal ◽  
Frans H. H. Leenen
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Spontaneously Hypertensive Rat ◽  
Blood Pressure Response ◽  
Receptor Occupancy ◽  
Pressure Response ◽  
Spontaneously Hypertensive ◽  
Wky Rats ◽  
Freely Moving ◽  
Wistar Kyoto

Blood pressure responsiveness to iv noradrenaline and angiotensin II was studied in conscious, freely moving, age-matched spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats from 4 to 16 weeks of age. At 4 and 6 weeks the SHR showed small, but nonsignificant increases in responsiveness compared with WKY to both noradrenaline and angiotensin II. At 8 weeks they exhibited similar responses to the WKY. Subsequently, at 12 and 16 weeks decreased responsiveness to noradrenaline (nonsignificant) and angiotensin II (p < 0.05 at 12 and 16 weeks) was observed in SHR versus WKY. At 16 weeks of age, hexamethonium caused potentiation of the blood pressure response to noradrenaline and angiotensin II, but to the same degree in the two strains. Captopril at this age did not elicit potentiation to noradrenaline or angiotensin II in either strain. These results indicate that there is no rise in blood pressure responsiveness to circulating pressor agents, parallel to the development of hypertension in SHR. Increased receptor occupancy or more active attenuating reflexes in SHR versus WKY appear not to be involved in the absence of hyperresponsiveness in intact consious SHR at 16 weeks of age.

Angiotensin I conversion and vascular reactivity in pathophysiological states in dogs

1980 ◽  
Vol 48 (2) ◽  
pp. 308-312 ◽  
Author(s):  
P. J. Leuenberger ◽  
S. A. Stalcup ◽  
L. M. Greenbaum ◽  
R. B. Mellins ◽  
G. M. Turino
Keyword(s):  
Blood Pressure ◽  
Enzyme Activity ◽  
Angiotensin Ii ◽  
Vascular Reactivity ◽  
Blood Pressure Response ◽  
Acute Hypoxia ◽  
Pressure Response ◽  
Converting Enzyme ◽  
Angiotensin I ◽  
Arterial Blood

To determine if angiotension converting enzyme activity is altered by acute pathophysiological insults, we assessed angiotensin I conversion using a blood pressure response technique in anesthetized dogs studied during acute 100% O2 breathing and acute acid-base derangements. Also, we determined systemic vascular reactivity to angiotensin II by measuring the magnitude and duration of the arterial blood pressure response to intra-arterial injections of angiotensin II under these same conditions. Angiotensin I conversion found in normoxia [91 +/- 7 (SD)%] was unchanged by acute acidosis, alkalosis, and hyperoxia. During acute hyperoxia the mean half time of the hypertensive response increased from 68 +/- 25 (SD) s at a PaO2 of 112 +/- 18 (SD) Torr to 100 +/- 34 (SD) s at a PaO2 of 491 +/- 47 (SD) Torr (P less than 0.01). No other pathophysiological condition studied had any effect on reactivity of systemic vasculature to angiotensin II. We conclude that, except during acute hypoxia as previously shown, converting enzyme activity is resistant to other pathophysiological insults and that vascular responsiveness to angiotensin II is enhanced by hyperoxia.

Sodium depletion and blood pressure response to 1-sarcosine, 8-isoleucine angiotensin II in hypertension

1978 ◽  
Vol 23 (5) ◽  
pp. 566-572 ◽  
Author(s):  
Toshio Ogihara ◽  
Takeshi Hata ◽  
Hiroshi Mikami ◽  
Mitsuaki Nakamaru ◽  
Anna Maruyama ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Sodium Depletion

scholarly journals Sex-Specific Effect of Endothelin in the Blood Pressure Response to Acute Angiotensin II in Growth-Restricted Rats

Hypertension ◽  
2015 ◽  
Vol 66 (6) ◽  
pp. 1260-1266 ◽  
Author(s):  
Suttira Intapad ◽  
Norma B. Ojeda ◽  
Elliott Varney ◽  
Thomas P. Royals ◽  
Barbara T. Alexander
Keyword(s):  
Blood Pressure ◽  
Angiotensin Ii ◽  
Blood Pressure Response ◽  
Specific Effect ◽  
Pressure Response
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