scholarly journals Vitamin D/Ca 2+ ‐dependent calpain and caspases: novel molecular targets for obesity‐related breast cancer drug discovery (261.5)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Igor Sergeev
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Drug Discovery ◽  
Molecular Targets ◽  
Cancer Drug ◽  
Cancer Drug Discovery

Abstract 2675: Characterization of human thioesterase 2 and its potential for breast cancer drug discovery

2010 ◽  
Author(s):  
Melissa K. Ritchie ◽  
Lynnette C. Johnson ◽  
Laura A. Watts ◽  
Steven J. Kridel ◽  
W. Todd Lowther
Keyword(s):  
Breast Cancer ◽  
Drug Discovery ◽  
Cancer Drug ◽  
Cancer Drug Discovery

scholarly journals STAT proteins: novel molecular targets for cancer drug discovery

Oncogene ◽  
2000 ◽  
Vol 19 (56) ◽  
pp. 6613-6626 ◽  
Author(s):  
James Turkson ◽  
Richard Jove
Keyword(s):  
Drug Discovery ◽  
Molecular Targets ◽  
Cancer Drug ◽  
Stat Proteins ◽  
Cancer Drug Discovery

scholarly journals Breast Cancer Drug Repurposing a Tool for a Challenging Disease

2022 ◽  
Author(s):  
Jonaid Ahmad Malik ◽  
Rafia Jan ◽  
Sakeel Ahmed ◽  
Sirajudheen Anwar
Keyword(s):  
Breast Cancer ◽  
Drug Discovery ◽  
Molecular Targets ◽  
Drug Repurposing ◽  
Current Therapy ◽  
Cancer Drug ◽  
Drug Development Process ◽  
Current Therapies ◽  
Treat Breast Cancer ◽  
Ovarian Syndrome

Drug repurposing is one of the best strategy for drug discovery. There are several examples where drug repurposing has revolutionized the drug development process, such as metformin developed for diabetes and is now employed in polycystic ovarian syndrome. Drug repurposing against breast cancer is currently a hot topic to look upon. With the continued rise in breast cancer cases, there is a dire need for new therapies that can tackle it in a better way. There is a rise of resistance to current therapies, so drug repurposing might produce some lead candidates that may be promising to treat breast cancer. We will highlight the breast cancer molecular targets, currently available drugs, problems with current therapy, and some examples that might be promising to treat it.

Innovative in vitro models for breast cancer drug discovery

2016 ◽  
Vol 21 ◽  
pp. 11-16 ◽  
Author(s):  
Elke Kaemmerer ◽  
Tayner E. Rodriguez Garzon ◽  
Aaron M. Lock ◽  
Carrie J. Lovitt ◽  
Vicky M. Avery
Keyword(s):  
Breast Cancer ◽  
Drug Discovery ◽  
In Vitro Models ◽  
Cancer Drug ◽  
Cancer Drug Discovery

scholarly journals Matrix metalloproteinase9 as the protein target in anti-breast cancer drug discovery: an approach by targeting hemopexin domain

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Christophorus Fideluno Adhipandito ◽  
Diana Putri Kartika Sari Ludji ◽  
Eko Aprilianto ◽  
Riris Istighfari Jenie ◽  
Belal Al-Najjar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Discovery ◽  
Cancer Drug ◽  
Protein Target ◽  
Cancer Drug Discovery ◽  
Hemopexin Domain
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