scholarly journals The N‐terminal region of the Trypanosoma brucei Tim17 is critical for mitochondrial protein import (950.3)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Ebony Weems
Keyword(s):  
Trypanosoma Brucei ◽  
Protein Import ◽  
Mitochondrial Protein ◽  
Terminal Region ◽  
Mitochondrial Protein Import

scholarly journals The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

mBio ◽  
2021 ◽  
Author(s):  
Uthman Okalang ◽  
Bar Mualem Bar-Ner ◽  
K. Shanmugha Rajan ◽  
Nehemya Friedman ◽  
Saurav Aryal ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Trypanosoma Brucei ◽  
Golgi Complex ◽  
Rna Silencing ◽  
Protein Import ◽  
Mitochondrial Protein ◽  
Sulfhydryl Oxidase ◽  
Mitochondrial Protein Import ◽  
Spliced Leader ◽  
Quiescin Sulfhydryl Oxidase

In this study, we found that SLS is induced by depletion of the essential ER-resident chaperones BiP and calreticulin, ER oxidoreductin 1 (ERO1), and the Golgi complex-localized quiescin sulfhydryl oxidase (QSOX). Most strikingly, silencing of Rhomboid-like 1 (TIMRHOM1), involved in mitochondrial protein import, also induces SLS.

scholarly journals Structural Basis of Presequence Recognition by the Mitochondrial Protein Import Receptor Tom20

Cell ◽  
2000 ◽  
Vol 100 (5) ◽  
pp. 551-560 ◽  
Author(s):  
Yoshito Abe ◽  
Toshihiro Shodai ◽  
Takanori Muto ◽  
Katsuyoshi Mihara ◽  
Hisayoshi Torii ◽  
...  
Keyword(s):  
Protein Import ◽  
Mitochondrial Protein ◽  
Structural Basis ◽  
Mitochondrial Protein Import ◽  
Import Receptor
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