Reversible shear-mediated platelet dysfunction during cardiac surgery as assessed by the PFA-100® platelet function analyzer

2001 ◽  
Vol 12 (2) ◽  
pp. 85-93 ◽  
Author(s):  
T. F. Slaughter ◽  
G. Sreeram ◽  
A. D. Sharma ◽  
H. El-Moalem ◽  
C. J. East ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Platelet Function ◽  
Platelet Dysfunction ◽  
Function Analyzer ◽  
Platelet Function Analyzer

scholarly journals The Role of Platelet Function Analyzer Testing in Cardiac Surgery Transfusion Management

2017 ◽  
Vol 44 (2) ◽  
pp. 106-113 ◽  
Author(s):  
Dejana Bogdanic ◽  
Nenad Karanovic ◽  
Jela Mratinovic-Mikulandra ◽  
Branka Paukovic-Sekulic ◽  
Dijana Brnic ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Platelet Function ◽  
Function Analyzer ◽  
Platelet Function Analyzer

Evaluation of multiple platelet function analyzer (Multiplate®) in cardiac surgery

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
C Schimmer ◽  
J Moser ◽  
K Hamouda ◽  
SP Sommer ◽  
M Bensch ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Platelet Function ◽  
Function Analyzer ◽  
Platelet Function Analyzer

scholarly journals Platelet Dysfunction in Primary Thrombocythemia Using the Platelet Function Analyzer, PFA-100

2005 ◽  
Vol 123 (5) ◽  
pp. 772-777 ◽  
Author(s):  
Jesús M. Cesar ◽  
Dunia de Miguel ◽  
Angel García Avello ◽  
Carmen Burgaleta
Keyword(s):  
Platelet Function ◽  
Platelet Dysfunction ◽  
Primary Thrombocythemia ◽  
Function Analyzer ◽  
Platelet Function Analyzer

SHEAR-MEDIATED PLATELET FUNCTION DURING CARDIAC SURGERY ASSESSED BY THE PFA-100[trade mark sign] (PLATELET FUNCTION ANALYZER)

1999 ◽  
Vol 88 (Supplement) ◽  
pp. 16SCA
Author(s):  
GM Sreeram ◽  
A Sharma ◽  
CJ East ◽  
H El-Moalem ◽  
&NA; Greenberg ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Platelet Function ◽  
Trade Mark ◽  
Function Analyzer ◽  
Platelet Function Analyzer

scholarly journals Adequate Platelet Function Inhibition Confirmed by Two Inductive Agents Predicts Lower Recurrence of Ischemic Stroke/Transient Ischemic Attack

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Lulu Zhang ◽  
Xiaowei Hu ◽  
Juehua Zhu ◽  
Xiuying Cai ◽  
Yan Kong ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Antiplatelet Therapy ◽  
Platelet Function ◽  
Adenosine Diphosphate ◽  
Aggregation Rate ◽  
Function Analyzer ◽  
Ischemic Attack ◽  
Platelet Function Analyzer ◽  
Platelet Functions

Background. The correlation between platelet function and recurrent ischemic stroke or TIA remains uncertain. Objective. To investigate two inductive agents to detect platelet functions and assess associations with recurrent ischemic stroke/TIA. Method. The study included 738 ischemic stroke/TIA patients. On days 0, 3, and 9 after antiplatelet therapy, platelet function tests were determined by maximum aggregation rate (MAR) using a PL-11 platelet function analyzer and phase matching reagents. Two induction agents were used: arachidonic acid (AA) and adenosine diphosphate (ADP). At 3-month follow-up, recurrence of stroke/TIA was recorded. Result. Cut-off values of adequate platelet function inhibition were MARADP < 35% and MARAA < 35%. Data showed that antiplatelet therapy could reduce the maximum aggregation rate. More importantly, adequate platelet function inhibition of either MARADP or MARAA was not associated with the recurrence of stroke/TIA, but adequate platelet function inhibition of not only MARADP but also MARAA predicts lower recurrence (0/121 (0.00%) versus 18/459 (3.92%), P = 0.0188). Conclusion. The platelet function tested by PL-11 demonstrated that adequate inhibition of both MARADP and MARAA could predict lower risk of ischemic stroke/TIA recurrence.

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