Treatment of Temporomandibular Disorders with Botulinum Toxin

2002 ◽  
Vol 18 (Supplement) ◽  
pp. S198-S203 ◽  
Author(s):  
Marvin Schwartz ◽  
Brian Freund
2018 ◽  
Vol 24 (3) ◽  
pp. 107-111 ◽  
Author(s):  
Alexis Kahn ◽  
Helios Bertin ◽  
Pierre Corre ◽  
Morgan Praud ◽  
Arnaud Paré ◽  
...  

Introduction: Temporomandibular disorders (TMD) are a common and invalidating disease sometimes difficult to treat. Current international recommendations favour reversible and non-invasive treatments, including the injection of botulinum toxin (BTX) into masticatory muscles. There is no strong evidence of its effectiveness. Objective: The main goal of this study was to assess the effectiveness of BTX six months following injection, in terms of pain, mouth opening, improvement of symptoms and duration of effect. Materials and methods: A retrospective study carried out at Nantes University Hospital between 2014 and 2016. Results: Thirty-four patients were included. The mean age was 37 years (17–76) and seventy six percents were female. Eighty percent of patients reported a significant improvement, notably in cases of arthralgia, which decreased in 8/18 (44%) patients (p < 0.05). The mean duration of measured efficacy was 4.2 months. Discussion: Significant improvement in cases of arthralgia and a tendency for improvement in cases of myalgia, with a mean duration of action of 4.2 months. Although BTX injection do not guarantee complete resolution of myofascial pain, it have been shown to have beneficial effects on some symptoms have been shown. Conclusion: Botulinum toxin should be considered as an alternative treatment when other conservative methods fail to yield satisfactory results. A thorough multicentre assessment is necessary in the future to scientifically validate its use.


BDJ ◽  
2019 ◽  
Vol 226 (9) ◽  
pp. 667-672 ◽  
Author(s):  
Jalpesh Patel ◽  
Jorge A. Cardoso ◽  
Shamir Mehta

2016 ◽  
Vol 04 (02) ◽  
pp. 081-087
Author(s):  
Mitasha Sachdeva ◽  
Vinay Dua ◽  
Puneet Gupta ◽  
Gaurav Ahuja

AbstractBotulinum toxin was first used therapeutically by a German physician Justinus Kerner (1786-1862). Trade name BOTOX was given by Allergan, Inc, Irvine, Calif for treating strabismus, blepharospasm, and hemifacial spasm. It is neurotoxin derived from an anaerobic bacteria Clostridium botulinum. The toxin inhibits the release of acetylcholine (ACH), a neurotransmitter responsible for the activation of muscle contraction and its administration results in diminution of tone in the injected muscle. It has found a variety of uses in dentistry like treatment of gummy smile, masseteric hypertrophy, bruxism, temporomandibular disorders and so on. It is a minimally invasive and cosmetically effective method of treating several conditions with excessive muscle contraction.


2000 ◽  
Vol 38 (5) ◽  
pp. 466-471 ◽  
Author(s):  
B. Freund ◽  
M. Schwartz ◽  
J.M. Symington

Author(s):  
Kyung-Hwan Kwon ◽  
Kyung Su Shin ◽  
Sung Hee Yeon ◽  
Dae Gun Kwon

Abstract Botulinum toxin (BTX) is used in various ways such as temporarily resolving muscular problems in musculoskeletal temporomandibular disorders, inducing a decrease in bruxism through a change in muscular patterns in a patient’s bruxism, and solving problems in patients with tension headache. And also, BTX is widely used in cosmetic applications for the treatment of facial wrinkles after local injection, but conditions such as temporomandibular joint disorders, headache, and neuropathic facial pain could be treated with this drug. In this report, we will discuss the clinical use of BTX for facial wrinkle, intraoral ulcer, and cranio-maxillofacial pain with previous studies and share our case.


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