Cardiac Markers and Point-of-Care Testing

2001 ◽  
Vol 24 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Ryan G. Males ◽  
Joanne Stephenson ◽  
Paul Harris
Keyword(s):  
Point Of Care ◽  
Cardiac Markers ◽  
Point Of Care Testing

Point-of-care testing of cardiac markers: results from an experience in an Emergency Department

2001 ◽  
Vol 311 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Sara Altinier ◽  
Martina Zaninotto ◽  
Monica Mion ◽  
Paolo Carraro ◽  
Stefano Rocco ◽  
...  
Keyword(s):  
Emergency Department ◽  
Point Of Care ◽  
Cardiac Markers ◽  
Point Of Care Testing

scholarly journals Point-of-Care Testing for Multiple Cardiac Markers Based on a Snail-Shaped Microfluidic Chip

2021 ◽  
Vol 9 ◽  
Author(s):  
Binfeng Yin ◽  
Xinhua Wan ◽  
Changcheng Qian ◽  
A. S. M. Muhtasim Fuad Sohan ◽  
Songbai Wang ◽  
...  
Keyword(s):  
Microfluidic Chip ◽  
Point Of Care ◽  
Mechanical Valve ◽  
High Sensitivity ◽  
Base Layer ◽  
Cardiac Markers ◽  
Point Of Care Testing ◽  
Experimental Conditions ◽  
Long Time ◽  
Low Sensitivity

Existing methods for detecting cardiac markers are difficult to be applied in point-of-care testing (POCT) due to complex operation, long time consumption, and low sensitivity. Here, we report a snail-shaped microfluidic chip (SMC) for the multiplex detection of cTnI, CK-MB, and Myo with high sensitivity and a short detection time. The SMC consists of a sandwich structure: a channel layer with a mixer and reaction zone, a reaction layer coated with capture antibodies, and a base layer. The opening or closing of the microchannels is realized by controlling the downward movement of the press-type mechanical valve. The chemiluminescence method was used as a signal readout, and the experimental conditions were optimized. SMC could detect cTnI, CK-MB, and Myo at concentrations as low as 1.02, 1.37, and 4.15. The SMC will be a promising platform for a simultaneous determination of multianalytes and shows a potential application in POCT.

Cardiac markers: point of care testing

1999 ◽  
Vol 284 (2) ◽  
pp. 223-237 ◽  
Author(s):  
Michael P. Hudson ◽  
Robert H. Christenson ◽  
L.Kristin Newby ◽  
Andrew L. Kaplan ◽  
E.Magnus Ohman
Keyword(s):  
Point Of Care ◽  
Cardiac Markers ◽  
Point Of Care Testing
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